ENSG00000078403


Homo sapiens

Features
Gene ID: ENSG00000078403
  
Biological name :MLLT10
  
Synonyms : MLLT10 / MLLT10, histone lysine methyltransferase DOT1L cofactor / P55197
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: p12.31
Gene start: 21524675
Gene end: 21743630
  
Corresponding Affymetrix probe sets: 1563321_s_at (Human Genome U133 Plus 2.0 Array)   205408_at (Human Genome U133 Plus 2.0 Array)   216480_x_at (Human Genome U133 Plus 2.0 Array)   216503_s_at (Human Genome U133 Plus 2.0 Array)   216506_x_at (Human Genome U133 Plus 2.0 Array)   216509_x_at (Human Genome U133 Plus 2.0 Array)   225992_at (Human Genome U133 Plus 2.0 Array)   230122_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000488569
Ensembl peptide - ENSP00000408281
Ensembl peptide - ENSP00000484335
Ensembl peptide - ENSP00000307411
Ensembl peptide - ENSP00000366258
Ensembl peptide - ENSP00000366272
Ensembl peptide - ENSP00000366295
Ensembl peptide - ENSP00000366304
Ensembl peptide - ENSP00000397800
Ensembl peptide - ENSP00000399883
NCBI entrez gene - 8028     See in Manteia.
OMIM - 602409
RefSeq - NM_001195627
RefSeq - NM_001195626
RefSeq - NM_001195628
RefSeq - NM_001195630
RefSeq - NM_001324296
RefSeq - NM_001324297
RefSeq - NM_004641
RefSeq Peptide - NP_001182556
RefSeq Peptide - NP_001311225
RefSeq Peptide - NP_001311226
RefSeq Peptide - NP_004632
RefSeq Peptide - NP_001182557
RefSeq Peptide - NP_001182555
RefSeq Peptide - NP_001182559
swissprot - H0Y5P4
swissprot - Q5JT35
swissprot - P55197
swissprot - H0Y5C4
Ensembl - ENSG00000078403
  
Related genetic diseases (OMIM): 601626 - Leukemia, acute myeloid, 601626
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mllt10ENSDARG00000045401Danio rerio
 MLLT10ENSGALG00000007928Gallus gallus
 Mllt10ENSMUSG00000026743Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MLLT6 / MLLT6, PHD finger containingENSG0000027502344
BRPF3 / Q9ULD4 / bromodomain and PHD finger containing 3ENSG0000009607017
BRPF1 / P55201 / bromodomain and PHD finger containing 1ENSG0000015698315
JADE3 / Q92613 / jade family PHD finger 3ENSG0000010222115
BRD1 / O95696 / bromodomain containing 1ENSG0000010042515
JADE1 / Q6IE81 / jade family PHD finger 1ENSG0000007768413
JADE2 / Q9NQC1 / jade family PHD finger 2ENSG0000004314313
PHF14 / O94880 / PHD finger protein 14ENSG0000010644311


Protein motifs (from Interpro)
Interpro ID Name
 IPR001965  Zinc finger, PHD-type
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR019786  Zinc finger, PHD-type, conserved site
 IPR019787  Zinc finger, PHD-finger
 IPR034732  Extended PHD (ePHD) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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