ENSG00000100425


Homo sapiens

Features
Gene ID: ENSG00000100425
  
Biological name :BRD1
  
Synonyms : BRD1 / bromodomain containing 1 / O95696
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: -1
Band: q13.33
Gene start: 49773283
Gene end: 49827512
  
Corresponding Affymetrix probe sets: 204520_x_at (Human Genome U133 Plus 2.0 Array)   215460_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000410042
Ensembl peptide - ENSP00000384076
Ensembl peptide - ENSP00000385858
Ensembl peptide - ENSP00000388027
Ensembl peptide - ENSP00000216267
NCBI entrez gene - 23774     See in Manteia.
OMIM - 604589
RefSeq - XM_017028723
RefSeq - XM_011530073
RefSeq - XM_017028714
RefSeq - XM_017028715
RefSeq - XM_017028716
RefSeq - XM_017028717
RefSeq - XM_017028718
RefSeq - XM_017028722
RefSeq - NM_001304808
RefSeq - NM_001304809
RefSeq - NM_001349941
RefSeq Peptide - NP_001336870
RefSeq Peptide - NP_001291737
RefSeq Peptide - NP_001291738
swissprot - A0A024R4V5
swissprot - O95696
swissprot - J3KQ61
swissprot - A0A024R4W4
Ensembl - ENSG00000100425
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 brd1aENSDARG00000013596Danio rerio
 brd1bENSDARG00000051798Danio rerio
 BRD1ENSGALG00000029379Gallus gallus
 Brd1ENSMUSG00000022387Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BRPF3 / Q9ULD4 / bromodomain and PHD finger containing 3ENSG0000009607054
BRPF1 / P55201 / bromodomain and PHD finger containing 1ENSG0000015698352
JADE3 / Q92613 / jade family PHD finger 3ENSG0000010222116
JADE1 / Q6IE81 / jade family PHD finger 1ENSG0000007768415
MLLT6 / MLLT6, PHD finger containingENSG0000027502314
JADE2 / Q9NQC1 / jade family PHD finger 2ENSG0000004314314
MLLT10 / P55197 / MLLT10, histone lysine methyltransferase DOT1L cofactorENSG0000007840314
PHF14 / O94880 / PHD finger protein 14ENSG0000010644313


Protein motifs (from Interpro)
Interpro ID Name
 IPR000313  PWWP domain
 IPR001487  Bromodomain
 IPR001965  Zinc finger, PHD-type
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR018359  Bromodomain, conserved site
 IPR019542  Enhancer of polycomb-like, N-terminal
 IPR019786  Zinc finger, PHD-type, conserved site
 IPR019787  Zinc finger, PHD-finger
 IPR034732  Extended PHD (ePHD) domain
 IPR035502  BR140-related, PWWD domain
 IPR036427  Bromodomain-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0035902 response to immobilization stress IEA
 biological_processGO:0043966 histone H3 acetylation IDA
 biological_processGO:0051602 response to electrical stimulus IEA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0043204 perikaryon IEA
 cellular_componentGO:0070776 MOZ/MORF histone acetyltransferase complex IDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0042393 histone binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
HATs acetylate histones
Regulation of TP53 Activity through Acetylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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