ENSG00000043143


Homo sapiens

Features
Gene ID: ENSG00000043143
  
Biological name :JADE2
  
Synonyms : JADE2 / jade family PHD finger 2 / Q9NQC1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q31.1
Gene start: 134524312
Gene end: 134583230
  
Corresponding Affymetrix probe sets: 208202_s_at (Human Genome U133 Plus 2.0 Array)   212660_at (Human Genome U133 Plus 2.0 Array)   232279_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000378451
Ensembl peptide - ENSP00000354425
Ensembl peptide - ENSP00000384671
Ensembl peptide - ENSP00000483173
Ensembl peptide - ENSP00000422991
Ensembl peptide - ENSP00000406189
Ensembl peptide - ENSP00000396026
Ensembl peptide - ENSP00000282605
NCBI entrez gene - 23338     See in Manteia.
OMIM - 610515
RefSeq - XM_017009282
RefSeq - NM_001289984
RefSeq - NM_001289985
RefSeq - NM_001308143
RefSeq - NM_015288
RefSeq - XM_005271945
RefSeq - XM_005271946
RefSeq - XM_005271948
RefSeq - XM_011543291
RefSeq Peptide - NP_001276913
RefSeq Peptide - NP_001276914
RefSeq Peptide - NP_001295072
RefSeq Peptide - NP_056103
swissprot - Q9NQC1
swissprot - A0A0C4DFT8
swissprot - G3XAA4
swissprot - H7C0P2
swissprot - B5MBX1
swissprot - A0A087X085
swissprot - D6R9B8
swissprot - C9J929
Ensembl - ENSG00000043143
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 jade2ENSDARG00000053389Danio rerio
 JADE2ENSGALG00000006424Gallus gallus
 Jade2ENSMUSG00000020387Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
JADE1 / Q6IE81 / jade family PHD finger 1ENSG0000007768449
JADE3 / Q92613 / jade family PHD finger 3ENSG0000010222140
BRPF3 / Q9ULD4 / bromodomain and PHD finger containing 3ENSG0000009607020
BRPF1 / P55201 / bromodomain and PHD finger containing 1ENSG0000015698320
BRD1 / O95696 / bromodomain containing 1ENSG0000010042520
MLLT6 / MLLT6, PHD finger containingENSG0000027502318
MLLT10 / P55197 / MLLT10, histone lysine methyltransferase DOT1L cofactorENSG0000007840317
PHF14 / O94880 / PHD finger protein 14ENSG0000010644315


Protein motifs (from Interpro)
Interpro ID Name
 IPR001965  Zinc finger, PHD-type
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR019542  Enhancer of polycomb-like, N-terminal
 IPR019786  Zinc finger, PHD-type, conserved site
 IPR019787  Zinc finger, PHD-finger
 IPR034732  Extended PHD (ePHD) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0043966 histone H3 acetylation IDA
 biological_processGO:0043981 histone H4-K5 acetylation IDA
 biological_processGO:0043982 histone H4-K8 acetylation IDA
 biological_processGO:0043983 histone H4-K12 acetylation IDA
 biological_processGO:0050767 regulation of neurogenesis IEA
 biological_processGO:0050769 positive regulation of neurogenesis IEA
 biological_processGO:0051865 protein autoubiquitination IEA
 biological_processGO:0060395 SMAD protein signal transduction IEA
 biological_processGO:1990138 neuron projection extension IEA
 cellular_componentGO:0000123 histone acetyltransferase complex IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
HATs acetylate histones


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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