ENSG00000079432


Homo sapiens

Features
Gene ID: ENSG00000079432
  
Biological name :CIC
  
Synonyms : capicua transcriptional repressor / CIC / Q96RK0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.2
Gene start: 42268537
Gene end: 42295797
  
Corresponding Affymetrix probe sets: 212784_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000459719
Ensembl peptide - ENSP00000459704
Ensembl peptide - ENSP00000460230
Ensembl peptide - ENSP00000160740
Ensembl peptide - ENSP00000458543
Ensembl peptide - ENSP00000458663
Ensembl peptide - ENSP00000459011
NCBI entrez gene - 23152     See in Manteia.
OMIM - 612082
RefSeq - XM_011526667
RefSeq - XM_005258674
RefSeq - XM_005258675
RefSeq - XM_011526660
RefSeq - XM_011526661
RefSeq - XM_011526662
RefSeq - XM_011526663
RefSeq - XM_011526664
RefSeq - XM_011526665
RefSeq - XM_011526666
RefSeq - NM_001304815
RefSeq - NM_015125
RefSeq - XM_005258673
RefSeq Peptide - NP_001291744
RefSeq Peptide - NP_055940
swissprot - I3L2I4
swissprot - I3L2J0
swissprot - I3L135
swissprot - Q96RK0
swissprot - A0A0A0MQR4
swissprot - I3L373
swissprot - I3L1Q4
Ensembl - ENSG00000079432
  
Related genetic diseases (OMIM): 617600 - Mental retardation, autosomal dominant 45, 617600

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cicaENSDARG00000071150Danio rerio
 cicbENSDARG00000055502Danio rerio
 CicENSMUSG00000005442Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BBX / Q8WY36 / BBX, HMG-box containingENSG000001144399


Protein motifs (from Interpro)
Interpro ID Name
 IPR009071  High mobility group box domain
 IPR032147  Domain of unknown function DUF4819
 IPR036910  High mobility group box domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0007612 learning IEA
 biological_processGO:0007613 memory IEA
 biological_processGO:0035176 social behavior IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0048286 lung alveolus development IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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