ENSG00000082512


Homo sapiens

Features
Gene ID: ENSG00000082512
  
Biological name :TRAF5
  
Synonyms : O00463 / TNF receptor associated factor 5 / TRAF5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q32.3
Gene start: 211326615
Gene end: 211374946
  
Corresponding Affymetrix probe sets: 1569861_at (Human Genome U133 Plus 2.0 Array)   204352_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000261464
Ensembl peptide - ENSP00000336825
Ensembl peptide - ENSP00000355971
NCBI entrez gene - 7188     See in Manteia.
OMIM - 602356
RefSeq - XM_017002221
RefSeq - NM_001033910
RefSeq - NM_001319207
RefSeq - NM_004619
RefSeq - NM_145759
RefSeq - XM_011509957
RefSeq - XM_011509959
RefSeq - XM_011509960
RefSeq Peptide - NP_001029082
RefSeq Peptide - NP_001306136
RefSeq Peptide - NP_004610
RefSeq Peptide - NP_665702
swissprot - O00463
Ensembl - ENSG00000082512
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 traf5ENSDARG00000017240Danio rerio
 TRAF5ENSGALG00000009864Gallus gallus
 Traf5ENSMUSG00000026637Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TRAF3 / Q13114 / TNF receptor associated factor 3ENSG0000013132342
TRAF2 / Q12933 / TNF receptor associated factor 2ENSG0000012719132
TRAF4 / Q9BUZ4 / TNF receptor associated factor 4ENSG0000007660424
TRAF6 / Q9Y4K3 / TNF receptor associated factor 6ENSG0000017510424
TRAF1 / Q13077 / TNF receptor associated factor 1ENSG0000005655823


Protein motifs (from Interpro)
Interpro ID Name
 IPR001293  Zinc finger, TRAF-type
 IPR001841  Zinc finger, RING-type
 IPR002083  MATH/TRAF domain
 IPR008974  TRAF-like
 IPR012227  TNF receptor-associated factor TRAF
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site
 IPR018957  Zinc finger, C3HC4 RING-type
 IPR027130  TNF receptor-associated factor 5
 IPR037308  TNF receptor-associated factor 5, MATH domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IEP
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IMP
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0009898 cytoplasmic side of plasma membrane ISS
 cellular_componentGO:0035631 CD40 receptor complex ISS
 molecular_functionGO:0005164 tumor necrosis factor receptor binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0031996 thioesterase binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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