ENSG00000083290


Homo sapiens

Features
Gene ID: ENSG00000083290
  
Biological name :ULK2
  
Synonyms : Q8IYT8 / ULK2 / unc-51 like autophagy activating kinase 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: p11.2
Gene start: 19770829
Gene end: 19867936
  
Corresponding Affymetrix probe sets: 1554112_a_at (Human Genome U133 Plus 2.0 Array)   204062_s_at (Human Genome U133 Plus 2.0 Array)   204063_s_at (Human Genome U133 Plus 2.0 Array)   215154_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000378914
Ensembl peptide - ENSP00000465666
Ensembl peptide - ENSP00000467277
Ensembl peptide - ENSP00000354877
Ensembl peptide - ENSP00000464892
NCBI entrez gene - 9706     See in Manteia.
OMIM - 608650
RefSeq - XM_017025428
RefSeq - NM_014683
RefSeq - XM_011524087
RefSeq - XM_017025424
RefSeq - XM_017025425
RefSeq - XM_017025426
RefSeq - XM_017025427
RefSeq - NM_001142610
RefSeq Peptide - NP_001136082
RefSeq Peptide - NP_055498
swissprot - K7EKK9
swissprot - K7EP89
swissprot - Q8IYT8
swissprot - K7EIU2
Ensembl - ENSG00000083290
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ulk2ENSDARG00000097205Danio rerio
 ULK2ENSGALG00000004727Gallus gallus
 Ulk2ENSMUSG00000004798Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ULK1 / O75385 / unc-51 like autophagy activating kinase 1ENSG0000017716954
ULK3 / Q6PHR2 / unc-51 like kinase 3ENSG0000014047415
CHUK / O15111 / conserved helix-loop-helix ubiquitous kinaseENSG0000021334115
IKBKB / O14920 / inhibitor of nuclear factor kappa B kinase subunit betaENSG0000010436514
IKBKE / Q14164 / inhibitor of nuclear factor kappa B kinase subunit epsilonENSG0000026352813
TBK1 / Q9UHD2 / TANK binding kinase 1ENSG0000018373512


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR016237  Serine/threonine-protein kinase, Ulk1/Ulk2
 IPR017441  Protein kinase, ATP binding site
 IPR022708  Serine/threonine-protein kinase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006914 autophagy IDA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007409 axonogenesis IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0042594 response to starvation IEA
 biological_processGO:0046777 protein autophosphorylation IDA
 biological_processGO:0048671 negative regulation of collateral sprouting IEA
 biological_processGO:0048675 axon extension IEA
 biological_processGO:0075044 autophagy of host cells involved in interaction with symbiont IGI
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0034045 phagophore assembly site membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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