ENSG00000084453


Homo sapiens

Features
Gene ID: ENSG00000084453
  
Biological name :SLCO1A2
  
Synonyms : P46721 / SLCO1A2 / solute carrier organic anion transporter family member 1A2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: p12.1
Gene start: 21264600
Gene end: 21419594
  
Corresponding Affymetrix probe sets: 207308_at (Human Genome U133 Plus 2.0 Array)   211480_s_at (Human Genome U133 Plus 2.0 Array)   211481_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000390672
Ensembl peptide - ENSP00000390572
Ensembl peptide - ENSP00000392124
Ensembl peptide - ENSP00000440154
Ensembl peptide - ENSP00000438348
Ensembl peptide - ENSP00000416190
Ensembl peptide - ENSP00000410338
Ensembl peptide - ENSP00000409691
Ensembl peptide - ENSP00000409314
Ensembl peptide - ENSP00000407462
Ensembl peptide - ENSP00000403638
Ensembl peptide - ENSP00000401195
Ensembl peptide - ENSP00000394854
Ensembl peptide - ENSP00000305974
NCBI entrez gene - 6579     See in Manteia.
OMIM - 602883
RefSeq - XM_017019850
RefSeq - NM_021094
RefSeq - NM_134431
RefSeq - XM_005253474
RefSeq - XM_005253477
RefSeq - XM_011520818
RefSeq - XM_011520819
RefSeq - XM_011520820
RefSeq - XM_011520821
RefSeq - XM_017019849
RefSeq Peptide - NP_602307
RefSeq Peptide - NP_066580
swissprot - F5H060
swissprot - P46721
swissprot - A0A024RAT5
swissprot - C9K059
swissprot - C9JUW6
swissprot - C9JTF6
swissprot - C9JSB7
swissprot - C9JHU9
swissprot - C9JGK7
swissprot - C9JG34
swissprot - C9JCA7
swissprot - B4DJE6
swissprot - C9IYW8
swissprot - F5GXY6
Ensembl - ENSG00000084453
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SLCO1A2ENSGALG00000031293Gallus gallus
 Gm5724ENSMUSG00000084927Mus musculus
 Q99J94ENSMUSG00000079262Mus musculus
 Q9EP96ENSMUSG00000030237Mus musculus
 Q9QXZ6ENSMUSG00000041698Mus musculus
 Slco1a5ENSMUSG00000063975Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9NYB5 / SLCO1C1 / solute carrier organic anion transporter family member 1C1ENSG0000013915544
Q9Y6L6 / SLCO1B1 / solute carrier organic anion transporter family member 1B1ENSG0000013453840
Q9NPD5 / SLCO1B3 / solute carrier organic anion transporter family member 1B3ENSG0000011170039
AC011604.2ENSG0000025704639
G3V0H7 / SLCO1B7 / solute carrier organic anion transporter family member 1B7 (putative)ENSG0000020575436
Q9UIG8 / SLCO3A1 / solute carrier organic anion transporter family member 3A1ENSG0000017646332
Q92959 / SLCO2A1 / solute carrier organic anion transporter family member 2A1ENSG0000017464031
Q9H2Y9 / SLCO5A1 / solute carrier organic anion transporter family member 5A1ENSG0000013757128
O94956 / SLCO2B1 / solute carrier organic anion transporter family member 2B1ENSG0000013749127
Q6ZQN7 / SLCO4C1 / solute carrier organic anion transporter family member 4C1ENSG0000017393026
Q96BD0 / SLCO4A1 / solute carrier organic anion transporter family member 4A1ENSG0000010118725
Q86UG4 / SLCO6A1 / solute carrier organic anion transporter family member 6A1ENSG0000020535920


Protein motifs (from Interpro)
Interpro ID Name
 IPR002350  Kazal domain
 IPR004156  Organic anion transporter polypeptide
 IPR020846  Major facilitator superfamily domain
 IPR027378  Cyclic nucleotide-regulated ion channel, N-terminal
 IPR036058  Kazal domain superfamily
 IPR036259  MFS transporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0015711 organic anion transport TAS
 biological_processGO:0015721 bile acid and bile salt transport TAS
 biological_processGO:0043252 sodium-independent organic anion transport TAS
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005215 transporter activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008514 organic anion transmembrane transporter activity TAS
 molecular_functionGO:0015125 bile acid transmembrane transporter activity TAS
 molecular_functionGO:0015347 sodium-independent organic anion transmembrane transporter activity IBA


Pathways (from Reactome)
Pathway description
Recycling of bile acids and salts
Transport of organic anions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000163631 ALB / P02768 / albumin  / reaction






 

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