ENSMUSG00000030237


Mus musculus

Features
Gene ID: ENSMUSG00000030237
  
Biological name :Slco1a4
  
Synonyms : Mus musculus solute carrier organic anion transporter family, member 1a4 (Slco1a4), transcript variant 2, mRNA. / Q9EP96 / Slco1a4
  
Possible biological names infered from orthology : P46721 / SLCO1A2 / solute carrier organic anion transporter family member 1A2
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: G2
Gene start: 141805440
Gene end: 141856199
  
Corresponding Affymetrix probe sets: 10548996 (MoGene1.0st)   1420405_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000032364
Ensembl peptide - ENSMUSP00000126767
Ensembl peptide - ENSMUSP00000130746
NCBI entrez gene - 28250     See in Manteia.
MGI - MGI:1351896
RefSeq - XM_017321610
RefSeq - NM_001355577
RefSeq - NM_030687
RefSeq - XM_006506962
RefSeq - XM_011241584
RefSeq - XM_011241585
RefSeq - XM_011241586
RefSeq - XM_006506960
RefSeq Peptide - NP_001342506
RefSeq Peptide - NP_109612
swissprot - Q9EP96
swissprot - E9PWV5
Ensembl - ENSMUSG00000030237
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SLCO1A2ENSGALG00000031293Gallus gallus
 P46721ENSG00000084453Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Slco1a5 / solute carrier organic anion transporter family, member 1a5 / P46721* / SLCO1A2* / solute carrier organic anion transporter family member 1A2*ENSMUSG0000006397584
Q9QXZ6 / Slco1a1 / solute carrier organic anion transporter family, member 1a1 / P46721* / SLCO1A2* / solute carrier organic anion transporter family member 1A2*ENSMUSG0000004169880
Gm5724 / P46721* / SLCO1A2* / solute carrier organic anion transporter family member 1A2*ENSMUSG0000008492777
Q99J94 / Slco1a6 / Solute carrier organic anion transporter family member 1A6 / P46721* / SLCO1A2* / solute carrier organic anion transporter family member 1A2*ENSMUSG0000007926275
Q9ERB5 / Slco1c1 / solute carrier organic anion transporter family, member 1c1 / Q9NYB5*ENSMUSG0000003023542
Q9JJL3 / Slco1b2 / Solute carrier organic anion transporter family member 1B2 / Q9Y6L6* / G3V0H7* / Q9NPD5* / SLCO1B1* / SLCO1B3* / SLCO1B7* / AC011604.2* / solute carrier organic anion tr...ENSMUSG0000003023639
Q8R3L5 / Slco3a1 / Solute carrier organic anion transporter family member 3A1 / Q9UIG8*ENSMUSG0000002579032
Q9EPT5 / Slco2a1 / solute carrier organic anion transporter family, member 2a1 / Q92959*ENSMUSG0000003254831
Q8BXB6 / Slco2b1 / solute carrier organic anion transporter family, member 2b1 / O94956*ENSMUSG0000003073728
Slco5a1 / solute carrier organic anion transporter family, member 5A1 / Q9H2Y9*ENSMUSG0000002593827
Q8K078 / Slco4a1 / Mus musculus solute carrier organic anion transporter family, member 4a1 (Slco4a1), transcript variant 2, mRNA. / Q96BD0* / solute carrier organic anion transporter famil...ENSMUSG0000003896327
Q8BGD4 / Slco4c1 / Solute carrier organic anion transporter family member 4C1 / Q6ZQN7*ENSMUSG0000004069327
Slco6c1 / solute carrier organic anion transporter family, member 6c1 / Q86UG4* / SLCO6A1* / solute carrier organic anion transporter family member 6A1*ENSMUSG0000002633120


Protein motifs (from Interpro)
Interpro ID Name
 IPR002350  Kazal domain
 IPR004156  Organic anion transporter polypeptide
 IPR020846  Major facilitator superfamily domain
 IPR027378  Cyclic nucleotide-regulated ion channel, N-terminal
 IPR036058  Kazal domain superfamily
 IPR036259  MFS transporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006820 anion transport IDA
 biological_processGO:0015711 organic anion transport IEA
 biological_processGO:0043252 sodium-independent organic anion transport IBA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005215 transporter activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008514 organic anion transmembrane transporter activity IDA
 molecular_functionGO:0015125 bile acid transmembrane transporter activity IEA
 molecular_functionGO:0015347 sodium-independent organic anion transmembrane transporter activity IBA


Pathways (from Reactome)
Pathway description
Recycling of bile acids and salts
Transport of organic anions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0009642 abnormal blood homeostasis "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions or chemical or protein composition of the blood" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Pink1tm1Hlw/Pink1tm1Hlw
Genetic Background: involves: 129 * C57BL/6J

 MP:0009643 abnormal urine homeostasis "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions and chemical or protein composition of the urine" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pink1tm1Hlw/Pink1tm1Hlw
Genetic Background: involves: 129 * C57BL/6J

 MP:0010080 abnormal hepatocyte physiology "any functional anomaly of the main structural specialized epithelial cells which normally organize into interconnected plates called lobules" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Pink1tm1Hlw/Pink1tm1Hlw
Genetic Background: involves: 129 * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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