ENSMUSG00000032548


Mus musculus

Features
Gene ID: ENSMUSG00000032548
  
Biological name :Slco2a1
  
Synonyms : Q9EPT5 / Slco2a1 / solute carrier organic anion transporter family, member 2a1
  
Possible biological names infered from orthology : Q92959
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: F1
Gene start: 102988712
Gene end: 103096002
  
Corresponding Affymetrix probe sets: 10588263 (MoGene1.0st)   1420913_at (Mouse Genome 430 2.0 Array)   1420914_at (Mouse Genome 430 2.0 Array)   1444242_at (Mouse Genome 430 2.0 Array)   1450032_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000035148
Ensembl peptide - ENSMUSP00000140533
NCBI entrez gene - 24059     See in Manteia.
MGI - MGI:1346021
RefSeq - XM_006511731
RefSeq - NM_033314
RefSeq Peptide - NP_201571
swissprot - Q3TED0
swissprot - Q9EPT5
Ensembl - ENSMUSG00000032548
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slco2a1ENSDARG00000061896Danio rerio
 SLCO2A1ENSGALG00000006471Gallus gallus
 Q92959ENSG00000174640Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8BXB6 / Slco2b1 / solute carrier organic anion transporter family, member 2b1 / O94956*ENSMUSG0000003073744
Q8R3L5 / Slco3a1 / Solute carrier organic anion transporter family member 3A1 / Q9UIG8*ENSMUSG0000002579034
Q9QXZ6 / Slco1a1 / solute carrier organic anion transporter family, member 1a1 / P46721* / SLCO1A2* / solute carrier organic anion transporter family member 1A2*ENSMUSG0000004169832
Q99J94 / Slco1a6 / Solute carrier organic anion transporter family member 1A6 / P46721* / SLCO1A2* / solute carrier organic anion transporter family member 1A2*ENSMUSG0000007926232
Slco1a5 / solute carrier organic anion transporter family, member 1a5 / P46721* / SLCO1A2* / solute carrier organic anion transporter family member 1A2*ENSMUSG0000006397532
Q9EP96 / Slco1a4 / Mus musculus solute carrier organic anion transporter family, member 1a4 (Slco1a4), transcript variant 2, mRNA. / P46721* / SLCO1A2* / solute carrier organic anion transp...ENSMUSG0000003023732
Q9ERB5 / Slco1c1 / solute carrier organic anion transporter family, member 1c1 / Q9NYB5*ENSMUSG0000003023531
Gm5724 / P46721* / SLCO1A2* / solute carrier organic anion transporter family member 1A2*ENSMUSG0000008492730
Q9JJL3 / Slco1b2 / Solute carrier organic anion transporter family member 1B2 / Q9Y6L6* / G3V0H7* / Q9NPD5* / SLCO1B1* / SLCO1B3* / SLCO1B7* / AC011604.2* / solute carrier organic anion tr...ENSMUSG0000003023630
Slco5a1 / solute carrier organic anion transporter family, member 5A1 / Q9H2Y9*ENSMUSG0000002593830
Q8BGD4 / Slco4c1 / Solute carrier organic anion transporter family member 4C1 / Q6ZQN7*ENSMUSG0000004069329
Q8K078 / Slco4a1 / Mus musculus solute carrier organic anion transporter family, member 4a1 (Slco4a1), transcript variant 2, mRNA. / Q96BD0* / solute carrier organic anion transporter famil...ENSMUSG0000003896327
Slco6c1 / solute carrier organic anion transporter family, member 6c1 / Q86UG4* / SLCO6A1* / solute carrier organic anion transporter family member 6A1*ENSMUSG0000002633119


Protein motifs (from Interpro)
Interpro ID Name
 IPR002350  Kazal domain
 IPR004156  Organic anion transporter polypeptide
 IPR020846  Major facilitator superfamily domain
 IPR036058  Kazal domain superfamily
 IPR036259  MFS transporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0015732 prostaglandin transport IDA
 biological_processGO:0043252 sodium-independent organic anion transport IBA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005215 transporter activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0015132 prostaglandin transmembrane transporter activity IDA
 molecular_functionGO:0015347 sodium-independent organic anion transmembrane transporter activity IBA


Pathways (from Reactome)
Pathway description
Transport of organic anions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002753 dilated left ventricle "an expansion in the volume of the lower left chamber of the heart" [J:82859, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Casp8tm1Hed/Casp8tm1Hed,Tg(KRT14-cre)1Efu/0
Genetic Background: Not Specified

Allelic Composition: Slco2a1tm1.2Vsch/Slco2a1tm1.2Vsch
Genetic Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * FVB/N

 MP:0002754 dilated right ventricle "an expansion in the volume of the lower right chamber of the heart" [J:82859, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Casp8tm1Hed/Casp8tm1Hed,Tg(KRT14-cre)1Efu/0
Genetic Background: Not Specified

Allelic Composition: Slco2a1tm1.2Vsch/Slco2a1tm1.2Vsch
Genetic Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * FVB/N

 MP:0003139 patent ductus arteriosus "failure of the fetal connection between the aorta and pulmonary artery to close within 24 hours after birth" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Casp8tm1Hed/Casp8tm1Hed,Tg(KRT14-cre)1Efu/0
Genetic Background: Not Specified

Allelic Composition: Slco2a1tm1.2Vsch/Slco2a1tm1.2Vsch
Genetic Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * FVB/N

 MP:0005621 abnormal cell physiology "aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
Show

Allelic Composition: Slco2a1tm1.2Vsch/Slco2a1tm1.2Vsch
Genetic Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * FVB/N

 MP:0009643 abnormal urine homeostasis "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions and chemical or protein composition of the urine" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Slco2a1tm1.2Vsch/Slco2a1tm1.2Vsch
Genetic Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * FVB/N

 MP:0009811 abnormal prostaglandin level "anomaly in the amount in the body of any of a class of mediators with effects of vasodilation, vasoconstriction, and smooth muscle stimulation" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Slco2a1tm1.2Vsch/Slco2a1tm1.2Vsch
Genetic Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * FVB/N

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Casp8tm1Hed/Casp8tm1Hed,Tg(KRT14-cre)1Efu/0
Genetic Background: Not Specified

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Slco2a1tm1.2Vsch/Slco2a1tm1.2Vsch
Genetic Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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