ENSG00000089558


Homo sapiens

Features
Gene ID: ENSG00000089558
  
Biological name :KCNH4
  
Synonyms : KCNH4 / potassium voltage-gated channel subfamily H member 4 / Q9UQ05
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q21.2
Gene start: 42156891
Gene end: 42181278
  
Corresponding Affymetrix probe sets: 220802_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000264661
Ensembl peptide - ENSP00000475564
NCBI entrez gene - 23415     See in Manteia.
OMIM - 604528
RefSeq - XM_017024402
RefSeq - NM_012285
RefSeq - XM_017024400
RefSeq - XM_017024401
RefSeq Peptide - NP_036417
swissprot - Q9UQ05
Ensembl - ENSG00000089558
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kcnh4aENSDARG00000062565Danio rerio
 kcnh4bENSDARG00000061990Danio rerio
 KCNH4ENSGALG00000003354Gallus gallus
 Kcnh4ENSMUSG00000035355Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KCNH8 / Q96L42 / potassium voltage-gated channel subfamily H member 8ENSG0000018396058
KCNH3 / Q9ULD8 / potassium voltage-gated channel subfamily H member 3ENSG0000013551951
KCNH7 / Q9NS40 / potassium voltage-gated channel subfamily H member 7ENSG0000018461136
KCNH2 / Q12809 / potassium voltage-gated channel subfamily H member 2ENSG0000005511836
KCNH6 / Q9H252 / potassium voltage-gated channel subfamily H member 6ENSG0000017382635
KCNH1 / O95259 / potassium voltage-gated channel subfamily H member 1ENSG0000014347332
KCNH5 / Q8NCM2 / potassium voltage-gated channel subfamily H member 5ENSG0000014001530
AL590132.1ENSG0000028429918
AC092017.3ENSG000002839523


Protein motifs (from Interpro)
Interpro ID Name
 IPR000014  PAS domain
 IPR000595  Cyclic nucleotide-binding domain
 IPR000700  PAS-associated, C-terminal
 IPR001610  PAC motif
 IPR003938  Potassium channel, voltage-dependent, EAG/ELK/ERG
 IPR003950  Potassium channel, voltage-dependent, ELK
 IPR005821  Ion transport domain
 IPR014710  RmlC-like jelly roll fold
 IPR018490  Cyclic nucleotide-binding-like
 IPR035965  PAS domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000160 phosphorelay signal transduction system IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport TAS
 biological_processGO:0023014 signal transduction by protein phosphorylation IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0042391 regulation of membrane potential IBA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0008076 voltage-gated potassium channel complex TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000155 phosphorelay sensor kinase activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity TAS
 molecular_functionGO:0005267 potassium channel activity IEA


Pathways (from Reactome)
Pathway description
Voltage gated Potassium channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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