ENSG00000135519


Homo sapiens

Features
Gene ID: ENSG00000135519
  
Biological name :KCNH3
  
Synonyms : KCNH3 / potassium voltage-gated channel subfamily H member 3 / Q9ULD8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q13.12
Gene start: 49539157
Gene end: 49558308
  
Corresponding Affymetrix probe sets: 223726_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000257981
NCBI entrez gene - 23416     See in Manteia.
OMIM - 604527
RefSeq - XM_017019097
RefSeq - NM_001314030
RefSeq - NM_012284
RefSeq - XM_011538085
RefSeq - XM_011538086
RefSeq - XM_017019096
RefSeq Peptide - NP_036416
RefSeq Peptide - NP_001300959
swissprot - Q9ULD8
Ensembl - ENSG00000135519
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kcnh3ENSDARG00000069560Danio rerio
 Kcnh3ENSMUSG00000037579Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KCNH8 / Q96L42 / potassium voltage-gated channel subfamily H member 8ENSG0000018396049
KCNH4 / Q9UQ05 / potassium voltage-gated channel subfamily H member 4ENSG0000008955848
KCNH2 / Q12809 / potassium voltage-gated channel subfamily H member 2ENSG0000005511831
KCNH7 / Q9NS40 / potassium voltage-gated channel subfamily H member 7ENSG0000018461130
KCNH6 / Q9H252 / potassium voltage-gated channel subfamily H member 6ENSG0000017382630
KCNH1 / O95259 / potassium voltage-gated channel subfamily H member 1ENSG0000014347329
KCNH5 / Q8NCM2 / potassium voltage-gated channel subfamily H member 5ENSG0000014001529
AL590132.1ENSG0000028429918
AC092017.3ENSG000002839523


Protein motifs (from Interpro)
Interpro ID Name
 IPR000014  PAS domain
 IPR000595  Cyclic nucleotide-binding domain
 IPR000700  PAS-associated, C-terminal
 IPR001610  PAC motif
 IPR003938  Potassium channel, voltage-dependent, EAG/ELK/ERG
 IPR003950  Potassium channel, voltage-dependent, ELK
 IPR005821  Ion transport domain
 IPR014710  RmlC-like jelly roll fold
 IPR018490  Cyclic nucleotide-binding-like
 IPR035965  PAS domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000160 phosphorelay signal transduction system IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport TAS
 biological_processGO:0023014 signal transduction by protein phosphorylation IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0042391 regulation of membrane potential IBA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane NAS
 molecular_functionGO:0000155 phosphorelay sensor kinase activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity TAS
 molecular_functionGO:0005267 potassium channel activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Voltage gated Potassium channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr