ENSG00000093000


Homo sapiens

Features
Gene ID: ENSG00000093000
  
Biological name :NUP50
  
Synonyms : nucleoporin 50 / NUP50 / Q9UKX7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q13.31
Gene start: 45163841
Gene end: 45188015
  
Corresponding Affymetrix probe sets: 213682_at (Human Genome U133 Plus 2.0 Array)   218293_x_at (Human Genome U133 Plus 2.0 Array)   218294_s_at (Human Genome U133 Plus 2.0 Array)   218295_s_at (Human Genome U133 Plus 2.0 Array)   222583_s_at (Human Genome U133 Plus 2.0 Array)   231064_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000391987
Ensembl peptide - ENSP00000416264
Ensembl peptide - ENSP00000415062
Ensembl peptide - ENSP00000400465
Ensembl peptide - ENSP00000398297
Ensembl peptide - ENSP00000397960
Ensembl peptide - ENSP00000394450
Ensembl peptide - ENSP00000345895
Ensembl peptide - ENSP00000379403
Ensembl peptide - ENSP00000385555
Ensembl peptide - ENSP00000388426
NCBI entrez gene - 10762     See in Manteia.
OMIM - 604646
RefSeq - XM_005261312
RefSeq - XM_017028537
RefSeq - XM_011529833
RefSeq - XM_006724104
RefSeq - XM_006724103
RefSeq - NM_007172
RefSeq - NM_153645
RefSeq - XM_005261314
RefSeq - XM_017028538
RefSeq Peptide - NP_705931
RefSeq Peptide - NP_009103
swissprot - X6RKQ2
swissprot - Q9UKX7
swissprot - B1AHA5
swissprot - F2Z3L9
swissprot - A0A024R4X7
swissprot - A0A0G2JI20
swissprot - A0A0G2JIF9
swissprot - B0QY21
Ensembl - ENSG00000093000
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nup50ENSDARG00000017454Danio rerio
 NUP50ENSGALG00000014222Gallus gallus
 1700123L14RikENSMUSG00000072878Mus musculus
 Nup50ENSMUSG00000016619Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000156  Ran binding domain
 IPR011993  PH-like domain superfamily
 IPR015007  Nuclear pore complex, NUP2/50/61


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006110 regulation of glycolytic process TAS
 biological_processGO:0006406 mRNA export from nucleus TAS
 biological_processGO:0006409 tRNA export from nucleus TAS
 biological_processGO:0006606 protein import into nucleus IBA
 biological_processGO:0007077 mitotic nuclear envelope disassembly TAS
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016032 viral process TAS
 biological_processGO:0016925 protein sumoylation TAS
 biological_processGO:0019083 viral transcription TAS
 biological_processGO:0046907 intracellular transport IEA
 biological_processGO:0051028 mRNA transport IEA
 biological_processGO:0060964 regulation of gene silencing by miRNA TAS
 biological_processGO:0075733 intracellular transport of virus TAS
 biological_processGO:1900034 regulation of cellular response to heat TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005643 nuclear pore IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031965 nuclear membrane IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0043657 host cell IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008536 Ran GTPase binding IBA


Pathways (from Reactome)
Pathway description
ISG15 antiviral mechanism
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
snRNP Assembly
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
tRNA processing in the nucleus


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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