Manteia

ENSMUSG00000016619

Mus musculus

Features

Gene ID:	ENSMUSG00000016619

Biological name :	Nup50

Synonyms :	Nuclear pore complex protein Nup50 / Nup50 / Q9JIH2

Possible biological names infered from orthology :	nucleoporin 50 / Q9UKX7

Species:	Mus musculus

Chr. number:	15
Strand:	1
Band:	E2
Gene start:	84923411
Gene end:	84942963

Corresponding Affymetrix probe sets:	10425905 (MoGene1.0st) 1422719_s_at (Mouse Genome 430 2.0 Array) 1428328_at (Mouse Genome 430 2.0 Array) 1450722_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000131457 Ensembl peptide - ENSMUSP00000155656 NCBI entrez gene - 18141 See in Manteia. MGI - MGI:1351502 RefSeq - NM_016714 RefSeq Peptide - NP_057923 swissprot - Q9JIH2 Ensembl - ENSMUSG00000016619

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
1700123L14Rik / RIKEN cDNA 1700123L14 gene / NUP50* / Q9UKX7* / nucleoporin 50*	ENSMUSG00000072878	53

Protein motifs (from Interpro)

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0001841	neural tube formation	IMP
biological_process	GO:0006606	protein import into nucleus	IBA
biological_process	GO:0015031	protein transport	IEA
biological_process	GO:0046907	intracellular transport	IEA
biological_process	GO:0051028	mRNA transport	IEA
cellular_component	GO:0005634	nucleus	IEA
cellular_component	GO:0005643	nuclear pore	IEA
cellular_component	GO:0005654	nucleoplasm	ISO
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0031965	nuclear membrane	ISS
cellular_component	GO:0043231	intracellular membrane-bounded organelle	ISO
molecular_function	GO:0005515	protein binding	IPI
molecular_function	GO:0008536	Ran GTPase binding	IBA

Pathways (from Reactome)

Pathway description

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0000914	exencephaly	"neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]	Show Allelic Composition: Prdm2^tm1Shg/Prdm2^tm1Shg,Trp53^tm1Tyj/Trp53⁺ Genetic Background: involves: 129S2/SvPas * C57BL/6
MP:0001698	reduced embryo size	"smaller proportions of embryo compared to littermates" [J:61790]	Show Allelic Composition: Prdm2^tm1Shg/Prdm2^tm1Shg,Trp53^tm1Tyj/Trp53⁺ Genetic Background: involves: 129S2/SvPas * C57BL/6
MP:0003400	kinked neural tube	"twists or kinks in the embryonic neural tube" [J:66514, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]	Show Allelic Composition: Prdm2^tm1Shg/Prdm2^tm1Shg,Trp53^tm1Tyj/Trp53⁺ Genetic Background: involves: 129S2/SvPas * C57BL/6
MP:0011089	complete perinatal lethality	"death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]	Show Allelic Composition: Prdm2^tm1Shg/Prdm2^tm1Shg,Trp53^tm1Tyj/Trp53⁺ Genetic Background: involves: 129S2/SvPas * C57BL/6

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr