ENSG00000095574


Homo sapiens

Features
Gene ID: ENSG00000095574
  
Biological name :IKZF5
  
Synonyms : IKAROS family zinc finger 5 / IKZF5 / Q9H5V7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: q26.13
Gene start: 122990806
Gene end: 123008817
  
Corresponding Affymetrix probe sets: 220086_at (Human Genome U133 Plus 2.0 Array)   226680_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000357881
Ensembl peptide - ENSP00000478056
NCBI entrez gene - 64376     See in Manteia.
OMIM - 606238
RefSeq - XM_017016555
RefSeq - NM_001271840
RefSeq - XM_017016553
RefSeq - XM_017016554
RefSeq - XM_006717947
RefSeq - XM_017016550
RefSeq - XM_017016551
RefSeq - XM_017016552
RefSeq Peptide - NP_001258769
swissprot - Q9H5V7
Ensembl - ENSG00000095574
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ikzf5ENSDARG00000056491Danio rerio
 IKZF5ENSGALG00000032289Gallus gallus
 Ikzf5ENSMUSG00000040167Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IKZF2 / Q9UKS7 / IKAROS family zinc finger 2ENSG0000003041924
IKZF4 / Q9H2S9 / IKAROS family zinc finger 4ENSG0000012341124
IKZF3 / Q9UKT9 / IKAROS family zinc finger 3ENSG0000016140523
IKZF1 / Q13422 / IKAROS family zinc finger 1ENSG0000018581123


Protein motifs (from Interpro)
Interpro ID Name
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0051291 protein heterooligomerization IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0032991 protein-containing complex IMP
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0008270 zinc ion binding IMP
 molecular_functionGO:0019904 protein domain specific binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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