ENSG00000161405


Homo sapiens

Features
Gene ID: ENSG00000161405
  
Biological name :IKZF3
  
Synonyms : IKAROS family zinc finger 3 / IKZF3 / Q9UKT9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q21.1
Gene start: 39757715
Gene end: 39864188
  
Corresponding Affymetrix probe sets: 221092_at (Human Genome U133 Plus 2.0 Array)   227030_at (Human Genome U133 Plus 2.0 Array)   236301_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000463505
Ensembl peptide - ENSP00000462791
Ensembl peptide - ENSP00000485515
Ensembl peptide - ENSP00000341977
Ensembl peptide - ENSP00000344471
Ensembl peptide - ENSP00000344544
Ensembl peptide - ENSP00000345622
Ensembl peptide - ENSP00000367179
Ensembl peptide - ENSP00000367180
Ensembl peptide - ENSP00000367188
Ensembl peptide - ENSP00000367194
Ensembl peptide - ENSP00000377741
Ensembl peptide - ENSP00000403027
Ensembl peptide - ENSP00000403776
Ensembl peptide - ENSP00000420463
Ensembl peptide - ENSP00000438972
Ensembl peptide - ENSP00000462452
NCBI entrez gene - 22806     See in Manteia.
OMIM - 606221
RefSeq - NM_183229
RefSeq - NM_001257408
RefSeq - NM_001257409
RefSeq - NM_001257410
RefSeq - NM_001257411
RefSeq - NM_001257412
RefSeq - NM_001257413
RefSeq - NM_001257414
RefSeq - NM_001284514
RefSeq - NM_001284515
RefSeq - NM_001284516
RefSeq - NM_012481
RefSeq - NM_183228
RefSeq - NM_183230
RefSeq - NM_183231
RefSeq - NM_183232
RefSeq Peptide - NP_899055
RefSeq Peptide - NP_001244337
RefSeq Peptide - NP_001244338
RefSeq Peptide - NP_001244339
RefSeq Peptide - NP_001244340
RefSeq Peptide - NP_001244341
RefSeq Peptide - NP_001244342
RefSeq Peptide - NP_001244343
RefSeq Peptide - NP_001271443
RefSeq Peptide - NP_001271444
RefSeq Peptide - NP_001271445
RefSeq Peptide - NP_036613
RefSeq Peptide - NP_899051
RefSeq Peptide - NP_899052
RefSeq Peptide - NP_899053
RefSeq Peptide - NP_899054
swissprot - Q9UKT9
swissprot - A0A0C4DGN9
Ensembl - ENSG00000161405
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IKZF3ENSGALG00000013481Gallus gallus
 Ikzf3ENSMUSG00000018168Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IKZF1 / Q13422 / IKAROS family zinc finger 1ENSG0000018581154
IKZF2 / Q9UKS7 / IKAROS family zinc finger 2ENSG0000003041948
IKZF4 / Q9H2S9 / IKAROS family zinc finger 4ENSG0000012341144
IKZF5 / Q9H5V7 / IKAROS family zinc finger 5ENSG0000009557419


Protein motifs (from Interpro)
Interpro ID Name
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II TAS
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007498 mesoderm development TAS
 biological_processGO:0030888 regulation of B cell proliferation ISS
 biological_processGO:0042113 B cell activation IEA
 biological_processGO:0042981 regulation of apoptotic process IMP
 biological_processGO:0045577 regulation of B cell differentiation ISS
 biological_processGO:0045619 regulation of lymphocyte differentiation ISS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IDA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0043565 sequence-specific DNA binding ISS
 molecular_functionGO:0044212 transcription regulatory region DNA binding IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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