ENSG00000123411


Homo sapiens

Features
Gene ID: ENSG00000123411
  
Biological name :IKZF4
  
Synonyms : IKAROS family zinc finger 4 / IKZF4 / Q9H2S9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q13.2
Gene start: 56007659
Gene end: 56038435
  
Corresponding Affymetrix probe sets: 208472_at (Human Genome U133 Plus 2.0 Array)   226759_at (Human Genome U133 Plus 2.0 Array)   226761_at (Human Genome U133 Plus 2.0 Array)   229752_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000449857
Ensembl peptide - ENSP00000449168
Ensembl peptide - ENSP00000450020
Ensembl peptide - ENSP00000262032
Ensembl peptide - ENSP00000412101
Ensembl peptide - ENSP00000448419
NCBI entrez gene - 64375     See in Manteia.
OMIM - 606239
RefSeq - XM_017019816
RefSeq - XM_017019808
RefSeq - XM_017019809
RefSeq - XM_017019810
RefSeq - XM_017019811
RefSeq - XM_017019812
RefSeq - XM_017019813
RefSeq - XM_017019814
RefSeq - XM_017019815
RefSeq - NM_001351089
RefSeq - NM_001351091
RefSeq - NM_022465
RefSeq - XM_005269086
RefSeq - XM_005269089
RefSeq - XM_005269090
RefSeq - XM_005269093
RefSeq - XM_011538664
RefSeq - XM_011538666
RefSeq - XM_011538669
RefSeq - XM_017019805
RefSeq - XM_017019806
RefSeq - XM_017019807
RefSeq Peptide - NP_071910
RefSeq Peptide - NP_001338018
RefSeq Peptide - NP_001338019
RefSeq Peptide - NP_001338020
swissprot - A0A0G2JL44
swissprot - F8VW19
swissprot - Q9H2S9
swissprot - F8VPL6
Ensembl - ENSG00000123411
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IKZF4ENSDARG00000037068Danio rerio
 IKZF4ENSGALG00000035734Gallus gallus
 Ikzf4ENSMUSG00000002578Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IKZF2 / Q9UKS7 / IKAROS family zinc finger 2ENSG0000003041950
IKZF1 / Q13422 / IKAROS family zinc finger 1ENSG0000018581144
IKZF3 / Q9UKT9 / IKAROS family zinc finger 3ENSG0000016140538
IKZF5 / Q9H5V7 / IKAROS family zinc finger 5ENSG0000009557417


Protein motifs (from Interpro)
Interpro ID Name
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated TAS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 biological_processGO:0051260 protein homooligomerization IMP
 biological_processGO:0051291 protein heterooligomerization IMP
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0016604 nuclear body IDA
 cellular_componentGO:0032991 protein-containing complex IMP
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0008270 zinc ion binding IMP
 molecular_functionGO:0019904 protein domain specific binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0043425 bHLH transcription factor binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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