ENSMUSG00000040167


Mus musculus

Features
Gene ID: ENSMUSG00000040167
  
Biological name :Ikzf5
  
Synonyms : Ikzf5 / Q8BU00 / Zinc finger protein Pegasus
  
Possible biological names infered from orthology : IKAROS family zinc finger 5 / Q9H5V7
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: F3
Gene start: 131388652
Gene end: 131410521
  
Corresponding Affymetrix probe sets: 10497996 (MoGene1.0st)   10568529 (MoGene1.0st)   1429431_at (Mouse Genome 430 2.0 Array)   1436554_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000113714
Ensembl peptide - ENSMUSP00000146590
Ensembl peptide - ENSMUSP00000139528
Ensembl peptide - ENSMUSP00000123530
Ensembl peptide - ENSMUSP00000117823
Ensembl peptide - ENSMUSP00000035583
NCBI entrez gene - 67143     See in Manteia.
MGI - MGI:1914393
RefSeq - XM_006508122
RefSeq - NM_175115
RefSeq Peptide - NP_780324
swissprot - A0A087WNW9
swissprot - D3YVZ8
swissprot - D3YYG0
swissprot - Q8BU00
swissprot - A0A140LHX6
Ensembl - ENSMUSG00000040167
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ikzf5ENSDARG00000056491Danio rerio
 IKZF5ENSGALG00000032289Gallus gallus
 IKZF5ENSG00000095574Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ikzf4 / Q8C208 / Mus musculus IKAROS family zinc finger 4 (Ikzf4), transcript variant 3, mRNA. / Q9H2S9* / IKAROS family zinc finger 4*ENSMUSG0000000257824
Ikzf2 / P81183 / Zinc finger protein Helios / Q9UKS7* / IKAROS family zinc finger 2*ENSMUSG0000002599724
Ikzf1 / IKAROS family zinc finger 1 / Q13422*ENSMUSG0000001865424
Ikzf3 / O08900 / Zinc finger protein Aiolos / Q9UKT9* / IKAROS family zinc finger 3*ENSMUSG0000001816824


Protein motifs (from Interpro)
Interpro ID Name
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISO
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0051291 protein heterooligomerization ISO
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding ISO
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding ISO
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0008270 zinc ion binding ISO
 molecular_functionGO:0019904 protein domain specific binding ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0010851 decreased effector memory CD8-positive, alpha-beta T cell number "reduced number of CD8-positive, alpha beta memory T cells with the phenotype CCR7-negative, CD127-positive, CD45RO-positive, and CD25-negative" [CL:0000913, GO_REF:0000031, GOC:add, GOC:pam, PMID:20146720]
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Allelic Composition: Gtpbp2tm1b(KOMP)Mbp/Gtpbp2+
Genetic Background: C57BL/6N-Gtpbp2tm1b(KOMP)Mbp/Ucd

 MP:0011967 increased or absent threshold for auditory brainstem response "increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith]
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Allelic Composition: Gtpbp2tm1b(KOMP)Mbp/Gtpbp2+
Genetic Background: C57BL/6N-Gtpbp2tm1b(KOMP)Mbp/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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