ENSG00000095596


Homo sapiens

Features
Gene ID: ENSG00000095596
  
Biological name :CYP26A1
  
Synonyms : CYP26A1 / cytochrome P450 family 26 subfamily A member 1 / O43174
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q23.33
Gene start: 93073475
Gene end: 93077890
  
Corresponding Affymetrix probe sets: 206424_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000224356
Ensembl peptide - ENSP00000485126
Ensembl peptide - ENSP00000360586
NCBI entrez gene - 1592     See in Manteia.
OMIM - 602239
RefSeq - NM_000783
RefSeq - NM_057157
RefSeq Peptide - NP_000774
RefSeq Peptide - NP_476498
swissprot - A0A096LNN2
swissprot - O43174
Ensembl - ENSG00000095596
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cyp26a1ENSDARG00000033999Danio rerio
 CYP26A1ENSGALG00000033695Gallus gallus
 Cyp26a1ENSMUSG00000024987Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6V0L0 / CYP26C1 / cytochrome P450 family 26 subfamily C member 1ENSG0000018755345
Q9NR63 / CYP26B1 / cytochrome P450 family 26 subfamily B member 1ENSG0000000313743
Q16850 / CYP51A1 / cytochrome P450 family 51 subfamily A member 1ENSG0000000163022


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002401  Cytochrome P450, E-class, group I
 IPR002403  Cytochrome P450, E-class, group IV
 IPR017972  Cytochrome P450, conserved site
 IPR036396  Cytochrome P450 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006766 vitamin metabolic process TAS
 biological_processGO:0006805 xenobiotic metabolic process IDA
 biological_processGO:0016125 sterol metabolic process IBA
 biological_processGO:0034653 retinoic acid catabolic process IDA
 biological_processGO:0042573 retinoic acid metabolic process IDA
 biological_processGO:0048387 negative regulation of retinoic acid receptor signaling pathway TAS
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031090 organelle membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0001972 retinoic acid binding IDA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0008401 retinoic acid 4-hydroxylase activity TAS
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen IDA
 molecular_functionGO:0019825 oxygen binding TAS
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Vitamins
RA biosynthesis pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000166426 CRABP1 / P29762 / cellular retinoic acid binding protein 1  / reaction






 

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