ENSG00000166426


Homo sapiens

Features
Gene ID: ENSG00000166426
  
Biological name :CRABP1
  
Synonyms : cellular retinoic acid binding protein 1 / CRABP1 / P29762
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q25.1
Gene start: 78340324
Gene end: 78348230
  
Corresponding Affymetrix probe sets: 205350_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000299529
Ensembl peptide - ENSP00000385978
NCBI entrez gene - 1381     See in Manteia.
OMIM - 180230
RefSeq - NM_004378
RefSeq Peptide - NP_004369
swissprot - B5MCB5
swissprot - F1T0F7
swissprot - P29762
Ensembl - ENSG00000166426
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 crabp1aENSDARG00000045926Danio rerio
 crabp1bENSDARG00000035904Danio rerio
 P40220ENSGALG00000003193Gallus gallus
 Crabp1ENSMUSG00000032291Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CRABP2 / P29373 / cellular retinoic acid binding protein 2ENSG0000014332076
RBP1 / P09455 / retinol binding protein 1ENSG0000011411541
PMP2 / P02689 / peripheral myelin protein 2ENSG0000014758841
FABP3 / P05413 / fatty acid binding protein 3ENSG0000012176939
RBP7 / Q96R05 / retinol binding protein 7ENSG0000016244437
FABP9 / Q0Z7S8 / fatty acid binding protein 9ENSG0000020518636
FABP4 / P15090 / fatty acid binding protein 4ENSG0000017032336
RBP5 / P82980 / retinol binding protein 5ENSG0000013919435
A6NFH5 / FABP12 / fatty acid binding protein 12ENSG0000019741635
RBP2 / P50120 / retinol binding protein 2ENSG0000011411334
FABP7 / O15540 / fatty acid binding protein 7ENSG0000016443434
FABP5 / Q01469 / fatty acid binding protein 5ENSG0000016468734


Protein motifs (from Interpro)
Interpro ID Name
 IPR000463  Cytosolic fatty-acid binding
 IPR000566  Lipocalin/cytosolic fatty-acid binding domain
 IPR012674  Calycin
 IPR031259  Intracellular lipid binding protein
 IPR031279  Cellular retinoic acid-binding protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007275 multicellular organism development TAS
 biological_processGO:0034653 retinoic acid catabolic process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0001972 retinoic acid binding IEA
 molecular_functionGO:0005501 retinoid binding TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0016918 retinal binding IEA
 molecular_functionGO:0019841 retinol binding IEA


Pathways (from Reactome)
Pathway description
RA biosynthesis pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000003137 Q9NR63 / CYP26B1 / cytochrome P450 family 26 subfamily B member 1  / reaction
 ENSG00000095596 O43174 / CYP26A1 / cytochrome P450 family 26 subfamily A member 1  / reaction
 ENSG00000187553 Q6V0L0 / CYP26C1 / cytochrome P450 family 26 subfamily C member 1  / reaction






 

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