ENSMUSG00000032291


Mus musculus

Features
Gene ID: ENSMUSG00000032291
  
Biological name :Crabp1
  
Synonyms : Cellular retinoic acid-binding protein 1 / Crabp1 / P62965
  
Possible biological names infered from orthology : P29762
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: A5.3
Gene start: 54764748
Gene end: 54773110
  
Corresponding Affymetrix probe sets: 10585438 (MoGene1.0st)   1448326_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000034830
NCBI entrez gene - 12903     See in Manteia.
MGI - MGI:88490
RefSeq - NM_013496
RefSeq - NM_001284507
RefSeq Peptide - NP_001271436
RefSeq Peptide - NP_038524
swissprot - P62965
Ensembl - ENSMUSG00000032291
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 crabp1aENSDARG00000045926Danio rerio
 crabp1bENSDARG00000035904Danio rerio
 P40220ENSGALG00000003193Gallus gallus
 CRABP1ENSG00000166426Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Crabp2 / P22935 / Cellular retinoic acid-binding protein 2 / P29373*ENSMUSG0000000488572
Fabp3 / P11404 / Fatty acid-binding protein, heart / P05413* / fatty acid binding protein 3*ENSMUSG0000002877342
Rbp1 / Q00915 / retinol binding protein 1, cellular / P09455* / retinol binding protein 1*ENSMUSG0000004640242
Pmp2 / P24526 / peripheral myelin protein 2 / P02689*ENSMUSG0000005246839
Fabp9 / O08716 / Fatty acid-binding protein 9 / Q0Z7S8*ENSMUSG0000002752839
Rbp7 / Q9EPC5 / retinol binding protein 7, cellular / Q96R05* / retinol binding protein 7*ENSMUSG0000002899639
Fabp4 / P04117 / Fatty acid-binding protein, adipocyte / P15090* / fatty acid binding protein 4*ENSMUSG0000006251536
Fabp12 / Q9DAK4 / Fatty acid-binding protein 12 / A6NFH5*ENSMUSG0000002753036
Fabp7 / P51880 / Fatty acid-binding protein, brain / O15540* / fatty acid binding protein 7*ENSMUSG0000001987436
Rbp2 / Q08652 / retinol binding protein 2, cellular / P50120* / retinol binding protein 2*ENSMUSG0000003245435
Fabp5 / Q05816 / Fatty acid-binding protein, epidermal / Q01469* / fatty acid binding protein 5*ENSMUSG0000002753333
Gm37389 / FABP9* / Q0Z7S8* / fatty acid binding protein 9*ENSMUSG0000010312428


Protein motifs (from Interpro)
Interpro ID Name
 IPR000463  Cytosolic fatty-acid binding
 IPR000566  Lipocalin/cytosolic fatty-acid binding domain
 IPR012674  Calycin
 IPR031259  Intracellular lipid binding protein
 IPR031279  Cellular retinoic acid-binding protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0034653 retinoic acid catabolic process IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0001972 retinoic acid binding IEA
 molecular_functionGO:0005501 retinoid binding TAS
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0016918 retinal binding IEA
 molecular_functionGO:0019841 retinol binding IEA


Pathways (from Reactome)
Pathway description
RA biosynthesis pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000562 polydactyly "greater than 5 digits on one or more autopods" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ighmtm1Cgn/Ighmtm1Cgn
Genetic Background: B6.129S2-Ighmtm1Cgn/J

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ighmtm1Cgn/Ighmtm1Cgn
Genetic Background: B6.129S2-Ighmtm1Cgn/J

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Scn8a5J/Scn8a5J
Genetic Background: C57BL/6J-Scn8a5J/J

Allelic Composition: Crabp1tm1Ipc/Crabp1tm1Ipc
Genetic Background: involves: 129S2/SvPas * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000024987 Cyp26a1 / cytochrome P450 family 26 subfamily A member 1 / O43174*  / reaction
 ENSMUSG00000063415 Q811W2 / Cyp26b1 / Cytochrome P450 26B1 / Q9NR63* / cytochrome P450 family 26 subfamily B member 1*  / reaction
 ENSMUSG00000062432 Cyp26c1 / cytochrome P450, family 26, subfamily c, polypeptide 1 / Q6V0L0* / cytochrome P450 family 26 subfamily C member 1*  / reaction






 

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