ENSMUSG00000052468


Mus musculus

Features
Gene ID: ENSMUSG00000052468
  
Biological name :Pmp2
  
Synonyms : P24526 / peripheral myelin protein 2 / Pmp2
  
Possible biological names infered from orthology : P02689
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: A1
Gene start: 10179851
Gene end: 10183929
  
Corresponding Affymetrix probe sets: 10497253 (MoGene1.0st)   1458193_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000029034
NCBI entrez gene - 18857     See in Manteia.
MGI - MGI:102667
RefSeq - NM_001030305
RefSeq Peptide - NP_001025476
swissprot - P24526
Ensembl - ENSMUSG00000052468
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01088982.1ENSDARG00000109259Danio rerio
 fabp11aENSDARG00000017299Danio rerio
 fabp11bENSDARG00000002311Danio rerio
 PMP2ENSGALG00000032453Gallus gallus
 PMP2ENSG00000147588Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fabp4 / P04117 / Fatty acid-binding protein, adipocyte / P15090* / fatty acid binding protein 4*ENSMUSG0000006251565
Fabp12 / Q9DAK4 / Fatty acid-binding protein 12 / A6NFH5*ENSMUSG0000002753061
Fabp9 / O08716 / Fatty acid-binding protein 9 / Q0Z7S8*ENSMUSG0000002752860
Fabp3 / P11404 / Fatty acid-binding protein, heart / P05413* / fatty acid binding protein 3*ENSMUSG0000002877358
Fabp7 / P51880 / Fatty acid-binding protein, brain / O15540* / fatty acid binding protein 7*ENSMUSG0000001987455
Fabp5 / Q05816 / Fatty acid-binding protein, epidermal / Q01469* / fatty acid binding protein 5*ENSMUSG0000002753351
Crabp1 / P62965 / Cellular retinoic acid-binding protein 1 / P29762*ENSMUSG0000003229140
Crabp2 / P22935 / Cellular retinoic acid-binding protein 2 / P29373*ENSMUSG0000000488539
Gm37389 / FABP9* / Q0Z7S8* / fatty acid binding protein 9*ENSMUSG0000010312437
Rbp7 / Q9EPC5 / retinol binding protein 7, cellular / Q96R05* / retinol binding protein 7*ENSMUSG0000002899637
Rbp1 / Q00915 / retinol binding protein 1, cellular / P09455* / retinol binding protein 1*ENSMUSG0000004640236
Rbp2 / Q08652 / retinol binding protein 2, cellular / P50120* / retinol binding protein 2*ENSMUSG0000003245434


Protein motifs (from Interpro)
Interpro ID Name
 IPR000463  Cytosolic fatty-acid binding
 IPR000566  Lipocalin/cytosolic fatty-acid binding domain
 IPR012674  Calycin
 IPR031256  Myelin P2 protein
 IPR031259  Intracellular lipid binding protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0061024 membrane organization IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0043209 myelin sheath IEA
 molecular_functionGO:0005504 fatty acid binding IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0015485 cholesterol binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000745 tremors "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Mbpshi/Mbpshi,Pmp2tm1.1(KOMP)Vlcg/Pmp2tm1.1(KOMP)Vlcg
Genetic Background: involves: C3HeB/FeJ * C57BL/6 * C57BL/6NTac

 MP:0001513 limb grasping "mice clasp front and/or hind feet almost immediately upon being lifted by tail" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
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Allelic Composition: Mbpshi/Mbpshi,Pmp2tm1.1(KOMP)Vlcg/Pmp2tm1.1(KOMP)Vlcg
Genetic Background: involves: C3HeB/FeJ * C57BL/6 * C57BL/6NTac

 MP:0002118 abnormal lipid homeostasis "anomaly in the state of equilibrium in the body with respect to lipids in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Asah1tm1Medin/Asah1tm1Medin
Genetic Background: involves: 129S6/SvEvTac * CD-1

 MP:0003871 abnormal myelin sheath morphology "malformation of the insulating envelope that surrounds nerve fibers or axons" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Mbpshi/Mbpshi,Pmp2tm1.1(KOMP)Vlcg/Pmp2tm1.1(KOMP)Vlcg
Genetic Background: involves: C3HeB/FeJ * C57BL/6 * C57BL/6NTac

 MP:0008814 reduced nerve conduction velocity "decrease in the rate at which an eletrical impulse travels through a nerve" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Asah1tm1Medin/Asah1tm1Medin
Genetic Background: involves: 129S6/SvEvTac * CD-1

Allelic Composition: Mbpshi/Mbpshi,Pmp2tm1.1(KOMP)Vlcg/Pmp2tm1.1(KOMP)Vlcg
Genetic Background: involves: C3HeB/FeJ * C57BL/6 * C57BL/6NTac

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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