ENSG00000170323


Homo sapiens

Features
Gene ID: ENSG00000170323
  
Biological name :FABP4
  
Synonyms : FABP4 / fatty acid binding protein 4 / P15090
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: q21.13
Gene start: 81478419
Gene end: 81483263
  
Corresponding Affymetrix probe sets: 203980_at (Human Genome U133 Plus 2.0 Array)   235978_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000256104
Ensembl peptide - ENSP00000428385
NCBI entrez gene - 2167     See in Manteia.
OMIM - 600434
RefSeq - NM_001442
RefSeq Peptide - NP_001433
swissprot - E7DVW4
swissprot - E5RIR0
swissprot - P15090
Ensembl - ENSG00000170323
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01088982.1ENSDARG00000109259Danio rerio
 fabp11aENSDARG00000017299Danio rerio
 fabp11bENSDARG00000002311Danio rerio
 FABP4ENSGALG00000030025Gallus gallus
 Fabp4ENSMUSG00000062515Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PMP2 / P02689 / peripheral myelin protein 2ENSG0000014758867
FABP9 / Q0Z7S8 / fatty acid binding protein 9ENSG0000020518664
FABP3 / P05413 / fatty acid binding protein 3ENSG0000012176964
A6NFH5 / FABP12 / fatty acid binding protein 12ENSG0000019741655
FABP7 / O15540 / fatty acid binding protein 7ENSG0000016443454
FABP5 / Q01469 / fatty acid binding protein 5ENSG0000016468753
RBP2 / P50120 / retinol binding protein 2ENSG0000011411339
RBP7 / Q96R05 / retinol binding protein 7ENSG0000016244439
CRABP1 / P29762 / cellular retinoic acid binding protein 1ENSG0000016642638
CRABP2 / P29373 / cellular retinoic acid binding protein 2ENSG0000014332037
RBP1 / P09455 / retinol binding protein 1ENSG0000011411536
RBP5 / P82980 / retinol binding protein 5ENSG0000013919429


Protein motifs (from Interpro)
Interpro ID Name
 IPR000463  Cytosolic fatty-acid binding
 IPR000566  Lipocalin/cytosolic fatty-acid binding domain
 IPR012674  Calycin
 IPR031259  Intracellular lipid binding protein
 IPR033073  Fatty acid-binding protein 4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001816 cytokine production IEA
 biological_processGO:0006469 negative regulation of protein kinase activity IEA
 biological_processGO:0019433 triglyceride catabolic process TAS
 biological_processGO:0042632 cholesterol homeostasis IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0050727 regulation of inflammatory response IEA
 biological_processGO:0050729 positive regulation of inflammatory response IEA
 biological_processGO:0050872 white fat cell differentiation IEA
 biological_processGO:0050873 brown fat cell differentiation IEA
 biological_processGO:0071285 cellular response to lithium ion IEA
 biological_processGO:0071356 cellular response to tumor necrosis factor IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005811 lipid droplet TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005504 fatty acid binding TAS
 molecular_functionGO:0008289 lipid binding IEA


Pathways (from Reactome)
Pathway description
Triglyceride catabolism
Transcriptional regulation of white adipocyte differentiation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000079435 LIPE / Q05469 / lipase E, hormone sensitive type  / complex / reaction






 

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