ENSG00000121769


Homo sapiens

Features
Gene ID: ENSG00000121769
  
Biological name :FABP3
  
Synonyms : FABP3 / fatty acid binding protein 3 / P05413
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p35.2
Gene start: 31365625
Gene end: 31376850
  
Corresponding Affymetrix probe sets: 205738_s_at (Human Genome U133 Plus 2.0 Array)   214285_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000362817
Ensembl peptide - ENSP00000473982
Ensembl peptide - ENSP00000474078
NCBI entrez gene - 2170     See in Manteia.
OMIM - 134651
RefSeq - NM_004102
RefSeq - NM_001320996
RefSeq Peptide - NP_001307925
RefSeq Peptide - NP_004093
swissprot - P05413
swissprot - S4R371
swissprot - S4R3A2
Ensembl - ENSG00000121769
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fabp3ENSDARG00000023290Danio rerio
 FABP3ENSGALG00000037050Gallus gallus
 Fabp3ENSMUSG00000028773Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FABP4 / P15090 / fatty acid binding protein 4ENSG0000017032364
PMP2 / P02689 / peripheral myelin protein 2ENSG0000014758862
FABP7 / O15540 / fatty acid binding protein 7ENSG0000016443460
FABP9 / Q0Z7S8 / fatty acid binding protein 9ENSG0000020518655
A6NFH5 / FABP12 / fatty acid binding protein 12ENSG0000019741651
FABP5 / Q01469 / fatty acid binding protein 5ENSG0000016468750
CRABP2 / P29373 / cellular retinoic acid binding protein 2ENSG0000014332043
CRABP1 / P29762 / cellular retinoic acid binding protein 1ENSG0000016642641
RBP2 / P50120 / retinol binding protein 2ENSG0000011411340
RBP7 / Q96R05 / retinol binding protein 7ENSG0000016244439
RBP5 / P82980 / retinol binding protein 5ENSG0000013919435
RBP1 / P09455 / retinol binding protein 1ENSG0000011411534


Protein motifs (from Interpro)
Interpro ID Name
 IPR000463  Cytosolic fatty-acid binding
 IPR000566  Lipocalin/cytosolic fatty-acid binding domain
 IPR012674  Calycin
 IPR031259  Intracellular lipid binding protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0008285 negative regulation of cell proliferation TAS
 biological_processGO:0015909 long-chain fatty acid transport IEA
 biological_processGO:0019433 triglyceride catabolic process TAS
 biological_processGO:0032868 response to insulin IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0042632 cholesterol homeostasis IEA
 biological_processGO:0044539 long-chain fatty acid import IEA
 biological_processGO:0046320 regulation of fatty acid oxidation IEA
 biological_processGO:0055091 phospholipid homeostasis IEA
 biological_processGO:0070542 response to fatty acid IEA
 biological_processGO:0071073 positive regulation of phospholipid biosynthetic process IC
 biological_processGO:2001245 regulation of phosphatidylcholine biosynthetic process IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016528 sarcoplasm IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005324 long-chain fatty acid transporter activity IEA
 molecular_functionGO:0005504 fatty acid binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008092 cytoskeletal protein binding IPI
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0036041 long-chain fatty acid binding IDA
 molecular_functionGO:0050543 icosatetraenoic acid binding IEA
 molecular_functionGO:0070538 oleic acid binding IDA


Pathways (from Reactome)
Pathway description
Triglyceride catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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