ENSG00000143320


Homo sapiens

Features
Gene ID: ENSG00000143320
  
Biological name :CRABP2
  
Synonyms : cellular retinoic acid binding protein 2 / CRABP2 / P29373
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q23.1
Gene start: 156699606
Gene end: 156705816
  
Corresponding Affymetrix probe sets: 202575_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000357203
Ensembl peptide - ENSP00000357204
Ensembl peptide - ENSP00000357205
Ensembl peptide - ENSP00000482841
NCBI entrez gene - 1382     See in Manteia.
OMIM - 180231
RefSeq - XM_017000343
RefSeq - NM_001199723
RefSeq - NM_001878
RefSeq Peptide - NP_001869
RefSeq Peptide - NP_001186652
swissprot - P29373
swissprot - Q5SYZ4
Ensembl - ENSG00000143320
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 crabp2aENSDARG00000073978Danio rerio
 crabp2bENSDARG00000030449Danio rerio
 CRABP2ENSGALG00000029140Gallus gallus
 Crabp2ENSMUSG00000004885Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CRABP1 / P29762 / cellular retinoic acid binding protein 1ENSG0000016642675
RBP1 / P09455 / retinol binding protein 1ENSG0000011411543
FABP3 / P05413 / fatty acid binding protein 3ENSG0000012176941
RBP7 / Q96R05 / retinol binding protein 7ENSG0000016244439
PMP2 / P02689 / peripheral myelin protein 2ENSG0000014758838
RBP5 / P82980 / retinol binding protein 5ENSG0000013919438
A6NFH5 / FABP12 / fatty acid binding protein 12ENSG0000019741637
FABP9 / Q0Z7S8 / fatty acid binding protein 9ENSG0000020518636
RBP2 / P50120 / retinol binding protein 2ENSG0000011411336
FABP4 / P15090 / fatty acid binding protein 4ENSG0000017032336
FABP7 / O15540 / fatty acid binding protein 7ENSG0000016443436
FABP5 / Q01469 / fatty acid binding protein 5ENSG0000016468733


Protein motifs (from Interpro)
Interpro ID Name
 IPR000463  Cytosolic fatty-acid binding
 IPR000566  Lipocalin/cytosolic fatty-acid binding domain
 IPR012674  Calycin
 IPR031259  Intracellular lipid binding protein
 IPR031281  Cellular retinoic acid-binding protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0008544 epidermis development TAS
 biological_processGO:0035115 embryonic forelimb morphogenesis IEA
 biological_processGO:0042573 retinoic acid metabolic process IEA
 biological_processGO:0048385 regulation of retinoic acid receptor signaling pathway IEA
 biological_processGO:0048672 positive regulation of collateral sprouting IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0001972 retinoic acid binding IEA
 molecular_functionGO:0005501 retinoid binding TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0016918 retinal binding IEA
 molecular_functionGO:0019841 retinol binding IEA


Pathways (from Reactome)
Pathway description
Signaling by Retinoic Acid


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000143171 RXRG / P48443 / retinoid X receptor gamma  / complex / reaction
 ENSG00000131759 RARA / P10276 / retinoic acid receptor alpha  / reaction / complex
 ENSG00000186350 RXRA / P19793 / retinoid X receptor alpha  / complex / reaction
 ENSG00000172819 RARG / P13631 / retinoic acid receptor gamma  / complex / reaction
 ENSG00000077092 RARB / P10826 / retinoic acid receptor beta  / complex / reaction
 ENSG00000204231 RXRB / P28702 / retinoid X receptor beta  / complex / reaction






 

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