ENSG00000099998


Homo sapiens

Features
Gene ID: ENSG00000099998
  
Biological name :GGT5
  
Synonyms : gamma-glutamyltransferase 5 / GGT5 / P36269
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: -1
Band: q11.23
Gene start: 24219654
Gene end: 24245142
  
Corresponding Affymetrix probe sets: 205582_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000263112
Ensembl peptide - ENSP00000381340
Ensembl peptide - ENSP00000402917
Ensembl peptide - ENSP00000412964
Ensembl peptide - ENSP00000330080
NCBI entrez gene - 2687     See in Manteia.
OMIM - 137168
RefSeq - XM_017028769
RefSeq - XM_005261557
RefSeq - XM_005261558
RefSeq - XM_011530133
RefSeq - XM_011530134
RefSeq - XM_011530135
RefSeq - XM_011530136
RefSeq - XM_011530137
RefSeq - XM_017028768
RefSeq - NM_001099781
RefSeq - NM_001099782
RefSeq - NM_001302464
RefSeq - NM_001302465
RefSeq - NM_004121
RefSeq Peptide - NP_001289394
RefSeq Peptide - NP_001093251
RefSeq Peptide - NP_001093252
RefSeq Peptide - NP_004112
RefSeq Peptide - NP_001289393
swissprot - P36269
swissprot - H7C1X2
swissprot - C9JU68
Ensembl - ENSG00000099998
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01049847.1ENSDARG00000078258Danio rerio
 ggt5aENSDARG00000052045Danio rerio
 GGT5ENSGALG00000040504Gallus gallus
 Ggt5ENSMUSG00000006344Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GGT1 / P19440 / gamma-glutamyltransferase 1ENSG0000010003139
GGT2 / P36268 / gamma-glutamyltransferase 2ENSG0000013347537
GGT7 / Q9UJ14 / gamma-glutamyltransferase 7ENSG0000013106727
GGT6 / Q6P531 / gamma-glutamyltransferase 6ENSG0000016774117
GGTLC1 / Q9BX51 / gamma-glutamyltransferase light chain 1ENSG0000014943515
B5MD39 / GGTLC3 / gamma-glutamyltransferase light chain family member 3ENSG0000027425214
GGTLC2 / Q14390 / gamma-glutamyltransferase light chain 2ENSG0000010012113


Protein motifs (from Interpro)
Interpro ID Name
 IPR000101  Gamma-glutamyltranspeptidase
 IPR029055  Nucleophile aminohydrolases, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006520 cellular amino acid metabolic process IDA
 biological_processGO:0006631 fatty acid metabolic process IDA
 biological_processGO:0006691 leukotriene metabolic process TAS
 biological_processGO:0006749 glutathione metabolic process IEA
 biological_processGO:0006750 glutathione biosynthetic process IEA
 biological_processGO:0006751 glutathione catabolic process IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0019370 leukotriene biosynthetic process IEA
 biological_processGO:1901750 leukotriene D4 biosynthetic process IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031226 intrinsic component of plasma membrane IDA
 molecular_functionGO:0000048 peptidyltransferase activity IDA
 molecular_functionGO:0002951 leukotriene-C(4) hydrolase IDA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036374 glutathione hydrolase activity IEA
 molecular_functionGO:0102953 hypoglycin A gamma-glutamyl transpeptidase activity IEA
 molecular_functionGO:0103068 leukotriene C4 gamma-glutamyl transferase activity IEA


Pathways (from Reactome)
Pathway description
Glutathione synthesis and recycling
Synthesis of Leukotrienes (LT) and Eoxins (EX)
Aflatoxin activation and detoxification


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000099998 GGT5 / P36269 / gamma-glutamyltransferase 5  / complex






 

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