ENSG00000133475


Homo sapiens

Features
Gene ID: ENSG00000133475
  
Biological name :GGT2
  
Synonyms : gamma-glutamyltransferase 2 / GGT2 / P36268
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: -1
Band: q11.21
Gene start: 21207973
Gene end: 21227637
  
Corresponding Affymetrix probe sets: 207131_x_at (Human Genome U133 Plus 2.0 Array)   208284_x_at (Human Genome U133 Plus 2.0 Array)   209919_x_at (Human Genome U133 Plus 2.0 Array)   211416_x_at (Human Genome U133 Plus 2.0 Array)   211417_x_at (Human Genome U133 Plus 2.0 Array)   215603_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000385721
Ensembl peptide - ENSP00000385601
NCBI entrez gene - 728441     See in Manteia.
OMIM - 137181
RefSeq - XM_017029186
RefSeq - XM_017029182
RefSeq - XM_017029185
RefSeq - XM_006724392
RefSeq - XM_006724395
RefSeq - XM_017029179
RefSeq - XM_017029180
RefSeq - XM_017029181
swissprot - P36268
swissprot - B5MCK8
Ensembl - ENSG00000133475
  
Related genetic diseases (OMIM): 137181 - [Gamma-glutamyltransferase, familial high serum]
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CU914631.1ENSDARG00000098576Danio rerio
 ggt1aENSDARG00000023526Danio rerio
 ggt1bENSDARG00000018342Danio rerio
 ggt1l2.1ENSDARG00000075055Danio rerio
 ggt1l2.2ENSDARG00000087054Danio rerio
 si:ch73-236c18.3ENSDARG00000075541Danio rerio
 si:ch73-59p9.2ENSDARG00000091254Danio rerio
 si:dkey-222h21.12ENSDARG00000092350Danio rerio
 ENSGALG00000006565Gallus gallus
 Ggt1ENSMUSG00000006345Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GGT1 / P19440 / gamma-glutamyltransferase 1ENSG0000010003195
B5MD39 / GGTLC3 / gamma-glutamyltransferase light chain family member 3ENSG0000027425239
GGT5 / P36269 / gamma-glutamyltransferase 5ENSG0000009999838
GGTLC1 / Q9BX51 / gamma-glutamyltransferase light chain 1ENSG0000014943535
GGTLC2 / Q14390 / gamma-glutamyltransferase light chain 2ENSG0000010012133
GGT7 / Q9UJ14 / gamma-glutamyltransferase 7ENSG0000013106728
GGT6 / Q6P531 / gamma-glutamyltransferase 6ENSG0000016774117


Protein motifs (from Interpro)
Interpro ID Name
 IPR000101  Gamma-glutamyltranspeptidase
 IPR029055  Nucleophile aminohydrolases, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006751 glutathione catabolic process IEA
 biological_processGO:1901750 leukotriene D4 biosynthetic process ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0036374 glutathione hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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