ENSG00000131067


Homo sapiens

Features
Gene ID: ENSG00000131067
  
Biological name :GGT7
  
Synonyms : gamma-glutamyltransferase 7 / GGT7 / Q9UJ14
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: q11.22
Gene start: 34844720
Gene end: 34872860
  
Corresponding Affymetrix probe sets: 226469_s_at (Human Genome U133 Plus 2.0 Array)   226470_at (Human Genome U133 Plus 2.0 Array)   226471_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000394993
Ensembl peptide - ENSP00000486589
Ensembl peptide - ENSP00000486190
Ensembl peptide - ENSP00000338964
NCBI entrez gene - 2686     See in Manteia.
OMIM - 612342
RefSeq - XM_017027811
RefSeq - NM_001351702
RefSeq - NM_178026
RefSeq - XM_011528782
RefSeq - XM_011528783
RefSeq - XM_017027809
RefSeq - XM_017027810
RefSeq Peptide - NP_001338631
RefSeq Peptide - NP_821158
swissprot - A2A2G5
swissprot - A0A0D9SFH0
swissprot - Q9UJ14
swissprot - A0A0D9SF08
Ensembl - ENSG00000131067
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GGT7ENSDARG00000115805Danio rerio
 GGT7ENSGALG00000001062Gallus gallus
 Ggt7ENSMUSG00000027603Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GGT1 / P19440 / gamma-glutamyltransferase 1ENSG0000010003126
GGT5 / P36269 / gamma-glutamyltransferase 5ENSG0000009999824
GGT2 / P36268 / gamma-glutamyltransferase 2ENSG0000013347524
GGT6 / Q6P531 / gamma-glutamyltransferase 6ENSG0000016774116
GGTLC1 / Q9BX51 / gamma-glutamyltransferase light chain 1ENSG0000014943510
B5MD39 / GGTLC3 / gamma-glutamyltransferase light chain family member 3ENSG000002742529
GGTLC2 / Q14390 / gamma-glutamyltransferase light chain 2ENSG000001001219


Protein motifs (from Interpro)
Interpro ID Name
 IPR000101  Gamma-glutamyltranspeptidase
 IPR029055  Nucleophile aminohydrolases, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006749 glutathione metabolic process IEA
 biological_processGO:0006750 glutathione biosynthetic process IEA
 biological_processGO:0006751 glutathione catabolic process IEA
 biological_processGO:1901750 leukotriene D4 biosynthetic process ISS
 biological_processGO:1902883 negative regulation of response to oxidative stress IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036374 glutathione hydrolase activity IEA
 molecular_functionGO:0102953 hypoglycin A gamma-glutamyl transpeptidase activity IEA
 molecular_functionGO:0103068 leukotriene C4 gamma-glutamyl transferase activity IEA


Pathways (from Reactome)
Pathway description
Glutathione synthesis and recycling
Aflatoxin activation and detoxification


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000131067 GGT7 / Q9UJ14 / gamma-glutamyltransferase 7  / complex






 

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