ENSG00000167741


Homo sapiens

Features
Gene ID: ENSG00000167741
  
Biological name :GGT6
  
Synonyms : gamma-glutamyltransferase 6 / GGT6 / Q6P531
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: p13.2
Gene start: 4556927
Gene end: 4560818
  
Corresponding Affymetrix probe sets: 236225_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000301395
Ensembl peptide - ENSP00000458307
Ensembl peptide - ENSP00000459662
Ensembl peptide - ENSP00000461230
Ensembl peptide - ENSP00000370962
NCBI entrez gene - 124975     See in Manteia.
OMIM - 612341
RefSeq - NM_001122890
RefSeq - NM_001288702
RefSeq - NM_001288703
RefSeq - NM_001288704
RefSeq - NM_153338
RefSeq Peptide - NP_001275632
RefSeq Peptide - NP_699169
RefSeq Peptide - NP_001116362
RefSeq Peptide - NP_001275631
RefSeq Peptide - NP_001275633
swissprot - I3L2G6
swissprot - Q6P531
swissprot - J3KPJ0
swissprot - B4DPG6
Ensembl - ENSG00000167741
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch73-337l15.2ENSDARG00000094268Danio rerio
 Ggt6ENSMUSG00000040471Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GGT7 / Q9UJ14 / gamma-glutamyltransferase 7ENSG0000013106721
GGT1 / P19440 / gamma-glutamyltransferase 1ENSG0000010003121
GGT5 / P36269 / gamma-glutamyltransferase 5ENSG0000009999820
GGT2 / P36268 / gamma-glutamyltransferase 2ENSG0000013347519
B5MD39 / GGTLC3 / gamma-glutamyltransferase light chain family member 3ENSG000002742526
GGTLC1 / Q9BX51 / gamma-glutamyltransferase light chain 1ENSG000001494356
GGTLC2 / Q14390 / gamma-glutamyltransferase light chain 2ENSG000001001215


Protein motifs (from Interpro)
Interpro ID Name
 IPR000101  Gamma-glutamyltranspeptidase
 IPR029055  Nucleophile aminohydrolases, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006749 glutathione metabolic process IEA
 biological_processGO:0006750 glutathione biosynthetic process IEA
 biological_processGO:0006751 glutathione catabolic process IEA
 biological_processGO:0008150 biological_process ND
 biological_processGO:1901750 leukotriene D4 biosynthetic process ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036374 glutathione hydrolase activity IEA
 molecular_functionGO:0102953 hypoglycin A gamma-glutamyl transpeptidase activity IEA
 molecular_functionGO:0103068 leukotriene C4 gamma-glutamyl transferase activity IEA


Pathways (from Reactome)
Pathway description
Glutathione synthesis and recycling
Aflatoxin activation and detoxification


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000167741 GGT6 / Q6P531 / gamma-glutamyltransferase 6  / complex






 

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