ENSG00000100568


Homo sapiens

Features
Gene ID: ENSG00000100568
  
Biological name :VTI1B
  
Synonyms : Q9UEU0 / vesicle transport through interaction with t-SNAREs 1B / VTI1B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q24.1
Gene start: 67647075
Gene end: 67674831
  
Corresponding Affymetrix probe sets: 209452_s_at (Human Genome U133 Plus 2.0 Array)   225926_at (Human Genome U133 Plus 2.0 Array)   225928_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000450731
Ensembl peptide - ENSP00000451661
Ensembl peptide - ENSP00000451759
Ensembl peptide - ENSP00000452366
Ensembl peptide - ENSP00000216456
NCBI entrez gene - 10490     See in Manteia.
OMIM - 603207
RefSeq - NM_006370
RefSeq Peptide - NP_006361
swissprot - Q9UEU0
swissprot - G3V5I2
swissprot - H0YJJ5
swissprot - H0YJL5
swissprot - J3KMW2
Ensembl - ENSG00000100568
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vti1bENSDARG00000039270Danio rerio
 VTI1BENSGALG00000009526Gallus gallus
 Vti1bENSMUSG00000021124Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
VTI1A / Q96AJ9 / vesicle transport through interaction with t-SNAREs 1AENSG0000015153228


Protein motifs (from Interpro)
Interpro ID Name
 IPR000727  Target SNARE coiled-coil homology domain
 IPR007705  Vesicle transport v-SNARE, N-terminal
 IPR010989  SNARE


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002576 platelet degranulation TAS
 biological_processGO:0006623 protein targeting to vacuole IBA
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport IBA
 biological_processGO:0006891 intra-Golgi vesicle-mediated transport IBA
 biological_processGO:0006896 Golgi to vacuole transport IBA
 biological_processGO:0006904 vesicle docking involved in exocytosis TAS
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport TAS
 biological_processGO:0042147 retrograde transport, endosome to Golgi IBA
 biological_processGO:0048280 vesicle fusion with Golgi apparatus IBA
 biological_processGO:0061025 membrane fusion TAS
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:1903076 regulation of protein localization to plasma membrane IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IBA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0008021 synaptic vesicle ISS
 cellular_componentGO:0012507 ER to Golgi transport vesicle membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031093 platelet alpha granule lumen TAS
 cellular_componentGO:0031201 SNARE complex IBA
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0031902 late endosome membrane IEA
 cellular_componentGO:0031982 vesicle IDA
 cellular_componentGO:0043025 neuronal cell body ISS
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:0055037 recycling endosome IDA
 cellular_componentGO:0055038 recycling endosome membrane IEA
 molecular_functionGO:0000149 SNARE binding IDA
 molecular_functionGO:0005484 SNAP receptor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019869 chloride channel inhibitor activity IDA


Pathways (from Reactome)
Pathway description
Platelet degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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