ENSG00000151532


Homo sapiens

Features
Gene ID: ENSG00000151532
  
Biological name :VTI1A
  
Synonyms : Q96AJ9 / vesicle transport through interaction with t-SNAREs 1A / VTI1A
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q25.2
Gene start: 112446998
Gene end: 112818744
  
Corresponding Affymetrix probe sets: 1552536_at (Human Genome U133 Plus 2.0 Array)   235034_at (Human Genome U133 Plus 2.0 Array)   235923_at (Human Genome U133 Plus 2.0 Array)   236849_at (Human Genome U133 Plus 2.0 Array)   242356_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000376792
Ensembl peptide - ENSP00000395017
NCBI entrez gene - 143187     See in Manteia.
OMIM - 614316
RefSeq - XM_017015748
RefSeq - NM_001318203
RefSeq - NM_001318205
RefSeq - NM_145206
RefSeq - XM_011539331
RefSeq - XM_017015745
RefSeq - XM_017015746
RefSeq - XM_017015747
RefSeq - XM_005269544
RefSeq - XM_005269545
RefSeq - XM_005269546
RefSeq - XM_005269547
RefSeq - XM_006717637
RefSeq - XM_011539328
RefSeq - XM_011539330
RefSeq Peptide - NP_001305134
RefSeq Peptide - NP_660207
RefSeq Peptide - NP_001305132
swissprot - Q96AJ9
Ensembl - ENSG00000151532
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vti1aENSDARG00000045065Danio rerio
 VTI1AENSGALG00000008880Gallus gallus
 Vti1aENSMUSG00000024983Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
VTI1B / Q9UEU0 / vesicle transport through interaction with t-SNAREs 1BENSG0000010056829


Protein motifs (from Interpro)
Interpro ID Name
 IPR000727  Target SNARE coiled-coil homology domain
 IPR007705  Vesicle transport v-SNARE, N-terminal
 IPR010989  SNARE
 IPR027027  GOSR2/Membrin/Bos1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006623 protein targeting to vacuole IBA
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport ISS
 biological_processGO:0006891 intra-Golgi vesicle-mediated transport IBA
 biological_processGO:0006896 Golgi to vacuole transport IBA
 biological_processGO:0006914 autophagy IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0042147 retrograde transport, endosome to Golgi IMP
 biological_processGO:0048280 vesicle fusion with Golgi apparatus ISS
 biological_processGO:0050882 voluntary musculoskeletal movement IMP
 biological_processGO:0090161 Golgi ribbon formation IMP
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005768 endosome ISS
 cellular_componentGO:0005776 autophagosome IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IBA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0008021 synaptic vesicle ISS
 cellular_componentGO:0012507 ER to Golgi transport vesicle membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030136 clathrin-coated vesicle ISS
 cellular_componentGO:0031201 SNARE complex ISS
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031902 late endosome membrane IBA
 cellular_componentGO:0032588 trans-Golgi network membrane TAS
 cellular_componentGO:0043025 neuronal cell body ISS
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0044306 neuron projection terminus ISS
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISS
 molecular_functionGO:0000149 SNARE binding IBA
 molecular_functionGO:0005484 SNAP receptor activity IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Intra-Golgi traffic
Retrograde transport at the Trans-Golgi-Network


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000104915 STX10 / O60499 / syntaxin 10  / complex
 ENSG00000105402 NAPA / P54920 / NSF attachment protein alpha  / complex / reaction
 ENSG00000135823 STX6 / O43752 / syntaxin 6  / complex
 ENSG00000197081 IGF2R / P11717 / insulin like growth factor 2 receptor  / reaction
 ENSG00000141252 VPS53 / Q5VIR6 / VPS53, GARP complex subunit  / reaction
 ENSG00000136933 Q7Z6M1 / RABEPK / Rab9 effector protein with kelch motifs  / reaction
 ENSG00000143952 VPS54 / Q9P1Q0 / VPS54, GARP complex subunit  / reaction
 ENSG00000223501 VPS52 / Q8N1B4 / VPS52, GARP complex subunit  / reaction
 ENSG00000049245 VAMP3 / Q15836 / vesicle associated membrane protein 3  / reaction / complex
 ENSG00000135968 GCC2 / Q8IWJ2 / GRIP and coiled-coil domain containing 2  / reaction
 ENSG00000117533 VAMP4 / O75379 / vesicle associated membrane protein 4  / complex
 ENSG00000149823 VPS51 / Q9UID3 / VPS51, GARP complex subunit  / reaction
 ENSG00000003056 M6PR / P20645 / mannose-6-phosphate receptor, cation dependent  / reaction
 ENSG00000123595 RAB9A / P51151 / RAB9A, member RAS oncogene family  / reaction
 ENSG00000073969 NSF / P46459 / N-ethylmaleimide sensitive factor, vesicle fusing ATPase  / complex / reaction
 ENSG00000124222 STX16 / O14662 / syntaxin 16  / complex






 

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