ENSG00000104915


Homo sapiens

Features
Gene ID: ENSG00000104915
  
Biological name :STX10
  
Synonyms : O60499 / STX10 / syntaxin 10
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.13
Gene start: 13144058
Gene end: 13150383
  
Corresponding Affymetrix probe sets: 212625_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000467713
Ensembl peptide - ENSP00000242770
Ensembl peptide - ENSP00000339350
Ensembl peptide - ENSP00000465398
Ensembl peptide - ENSP00000464970
Ensembl peptide - ENSP00000464943
Ensembl peptide - ENSP00000415176
Ensembl peptide - ENSP00000465495
Ensembl peptide - ENSP00000466272
Ensembl peptide - ENSP00000466298
Ensembl peptide - ENSP00000467479
NCBI entrez gene - 8677     See in Manteia.
OMIM - 603765
RefSeq - NM_001271609
RefSeq - NM_001271611
RefSeq - NM_003765
RefSeq - NM_001271610
RefSeq Peptide - NP_001258540
RefSeq Peptide - NP_001258539
RefSeq Peptide - NP_001258538
RefSeq Peptide - NP_003756
swissprot - X6R2W0
swissprot - F6RTM7
swissprot - K7EIY4
swissprot - K7EJ05
swissprot - K7EK75
swissprot - K7ELY2
swissprot - K7EPP9
swissprot - K7EQ84
swissprot - O60499
swissprot - Q5U8S2
Ensembl - ENSG00000104915
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stx10ENSDARG00000075030Danio rerio
 stx10ENSDARG00000114081Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
STX6 / O43752 / syntaxin 6ENSG0000013582362


Protein motifs (from Interpro)
Interpro ID Name
 IPR000727  Target SNARE coiled-coil homology domain
 IPR006012  Syntaxin/epimorphin, conserved site
 IPR010989  SNARE
 IPR015260  Syntaxin 6, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006906 vesicle fusion IBA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0032880 regulation of protein localization IMP
 biological_processGO:0042147 retrograde transport, endosome to Golgi IDA
 biological_processGO:0048193 Golgi vesicle transport IEA
 biological_processGO:0048278 vesicle docking IBA
 biological_processGO:0061025 membrane fusion IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005802 trans-Golgi network IDA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 cellular_componentGO:0031201 SNARE complex IBA
 cellular_componentGO:0031982 vesicle IDA
 cellular_componentGO:0032588 trans-Golgi network membrane TAS
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0005484 SNAP receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019905 syntaxin binding IPI


Pathways (from Reactome)
Pathway description
Retrograde transport at the Trans-Golgi-Network


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000123595 RAB9A / P51151 / RAB9A, member RAS oncogene family  / reaction
 ENSG00000003056 M6PR / P20645 / mannose-6-phosphate receptor, cation dependent  / reaction
 ENSG00000073969 NSF / P46459 / N-ethylmaleimide sensitive factor, vesicle fusing ATPase  / complex / reaction
 ENSG00000149823 VPS51 / Q9UID3 / VPS51, GARP complex subunit  / reaction
 ENSG00000197081 IGF2R / P11717 / insulin like growth factor 2 receptor  / reaction
 ENSG00000124222 STX16 / O14662 / syntaxin 16  / complex
 ENSG00000143952 VPS54 / Q9P1Q0 / VPS54, GARP complex subunit  / reaction
 ENSG00000151532 VTI1A / Q96AJ9 / vesicle transport through interaction with t-SNAREs 1A  / complex
 ENSG00000141252 VPS53 / Q5VIR6 / VPS53, GARP complex subunit  / reaction
 ENSG00000136933 Q7Z6M1 / RABEPK / Rab9 effector protein with kelch motifs  / reaction
 ENSG00000049245 VAMP3 / Q15836 / vesicle associated membrane protein 3  / complex / reaction
 ENSG00000223501 VPS52 / Q8N1B4 / VPS52, GARP complex subunit  / reaction
 ENSG00000135968 GCC2 / Q8IWJ2 / GRIP and coiled-coil domain containing 2  / reaction
 ENSG00000105402 NAPA / P54920 / NSF attachment protein alpha  / reaction / complex






 

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