ENSG00000143952


Homo sapiens

Features
Gene ID: ENSG00000143952
  
Biological name :VPS54
  
Synonyms : Q9P1Q0 / VPS54 / VPS54, GARP complex subunit
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: p14
Gene start: 63892146
Gene end: 64019072
  
Corresponding Affymetrix probe sets: 218423_x_at (Human Genome U133 Plus 2.0 Array)   222627_at (Human Genome U133 Plus 2.0 Array)   233656_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000414725
Ensembl peptide - ENSP00000272322
Ensembl peptide - ENSP00000346499
Ensembl peptide - ENSP00000386980
NCBI entrez gene - 51542     See in Manteia.
OMIM - 614633
RefSeq - XM_017004316
RefSeq - NM_001005739
RefSeq - NM_016516
RefSeq - XM_006712029
RefSeq Peptide - NP_057600
RefSeq Peptide - NP_001005739
swissprot - Q9P1Q0
swissprot - A0A0A0MT48
Ensembl - ENSG00000143952
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vps54ENSDARG00000102960Danio rerio
 VPS54ENSGALG00000008847Gallus gallus
 Vps54ENSMUSG00000020128Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR012501  Vps54-likeVacuolar protein sorting-associated protein 54, C-terminal
 IPR019515  Vacuolar protein sorting-associated protein 54, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006896 Golgi to vacuole transport IBA
 biological_processGO:0007041 lysosomal transport IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0040007 growth IEA
 biological_processGO:0042147 retrograde transport, endosome to Golgi IEA
 biological_processGO:0048873 homeostasis of number of cells within a tissue IEA
 biological_processGO:0050881 musculoskeletal movement IEA
 biological_processGO:0060052 neurofilament cytoskeleton organization IEA
 cellular_componentGO:0000938 GARP complex IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005802 trans-Golgi network IMP
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0032588 trans-Golgi network membrane TAS
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019905 syntaxin binding IBA


Pathways (from Reactome)
Pathway description
Retrograde transport at the Trans-Golgi-Network


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000003056 M6PR / P20645 / mannose-6-phosphate receptor, cation dependent  / reaction
 ENSG00000049245 VAMP3 / Q15836 / vesicle associated membrane protein 3  / reaction
 ENSG00000123595 RAB9A / P51151 / RAB9A, member RAS oncogene family  / reaction
 ENSG00000104915 STX10 / O60499 / syntaxin 10  / reaction
 ENSG00000136933 Q7Z6M1 / RABEPK / Rab9 effector protein with kelch motifs  / reaction
 ENSG00000149823 VPS51 / Q9UID3 / VPS51, GARP complex subunit  / complex
 ENSG00000223501 VPS52 / Q8N1B4 / VPS52, GARP complex subunit  / complex
 ENSG00000141252 VPS53 / Q5VIR6 / VPS53, GARP complex subunit  / complex
 ENSG00000124222 STX16 / O14662 / syntaxin 16  / reaction
 ENSG00000135968 GCC2 / Q8IWJ2 / GRIP and coiled-coil domain containing 2  / reaction
 ENSG00000197081 IGF2R / P11717 / insulin like growth factor 2 receptor  / reaction
 ENSG00000151532 VTI1A / Q96AJ9 / vesicle transport through interaction with t-SNAREs 1A  / reaction






 

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