ENSG00000136933


Homo sapiens

Features
Gene ID: ENSG00000136933
  
Biological name :RABEPK
  
Synonyms : Q7Z6M1 / Rab9 effector protein with kelch motifs / RABEPK
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: q33.3
Gene start: 125200542
Gene end: 125234158
  
Corresponding Affymetrix probe sets: 1558021_at (Human Genome U133 Plus 2.0 Array)   203150_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000377683
Ensembl peptide - ENSP00000362645
Ensembl peptide - ENSP00000402234
Ensembl peptide - ENSP00000487422
Ensembl peptide - ENSP00000259460
Ensembl peptide - ENSP00000362639
NCBI entrez gene - 10244     See in Manteia.
OMIM - 605962
RefSeq - XM_017014183
RefSeq - XM_005251644
RefSeq - XM_011518120
RefSeq - XM_017014177
RefSeq - XM_017014178
RefSeq - XM_017014179
RefSeq - XM_017014180
RefSeq - XM_017014181
RefSeq - XM_017014182
RefSeq - NM_001174152
RefSeq - NM_001174153
RefSeq - NM_005833
RefSeq - XM_005251640
RefSeq - XM_005251641
RefSeq - XM_005251642
RefSeq Peptide - NP_001167624
RefSeq Peptide - NP_005824
RefSeq Peptide - NP_001167623
swissprot - A0A024R8A0
swissprot - A0A0S2Z4Z5
swissprot - Q5T1S4
swissprot - Q5T1S5
swissprot - Q7Z6M1
Ensembl - ENSG00000136933
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q6GQN7ENSDARG00000112165Danio rerio
 RABEPKENSGALG00000042210Gallus gallus
 Q8VCH5ENSMUSG00000070953Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HCFC2 / Q9Y5Z7 / host cell factor C2ENSG0000011172727
HCFC1 / P51610 / host cell factor C1ENSG0000017253427
KLHDC2 / Q9Y2U9 / kelch domain containing 2ENSG0000016551621
KLHDC3 / Q9BQ90 / kelch domain containing 3ENSG0000012470220
LZTR1 / Q8N653 / leucine zipper like transcription regulator 1ENSG0000009994920
KLHDC1 / Q8N7A1 / kelch domain containing 1ENSG0000019777619
Q6PID8 / KLHDC10 / kelch domain containing 10ENSG0000012860717


Protein motifs (from Interpro)
Interpro ID Name
 IPR006652  Kelch repeat type 1
 IPR011498  Kelch repeat type 2
 IPR015915  Kelch-type beta propeller
 IPR037293  Galactose oxidase, central domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006898 receptor-mediated endocytosis TAS
 biological_processGO:0006904 vesicle docking involved in exocytosis TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030133 transport vesicle TAS
 cellular_componentGO:0032588 trans-Golgi network membrane TAS
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Retrograde transport at the Trans-Golgi-Network


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000003056 M6PR / P20645 / mannose-6-phosphate receptor, cation dependent  / complex
 ENSG00000049245 VAMP3 / Q15836 / vesicle associated membrane protein 3  / complex
 ENSG00000104915 STX10 / O60499 / syntaxin 10  / reaction
 ENSG00000149823 VPS51 / Q9UID3 / VPS51, GARP complex subunit  / reaction
 ENSG00000141252 VPS53 / Q5VIR6 / VPS53, GARP complex subunit  / reaction
 ENSG00000123595 RAB9A / P51151 / RAB9A, member RAS oncogene family  / complex
 ENSG00000143952 VPS54 / Q9P1Q0 / VPS54, GARP complex subunit  / reaction
 ENSG00000223501 VPS52 / Q8N1B4 / VPS52, GARP complex subunit  / reaction
 ENSG00000124222 STX16 / O14662 / syntaxin 16  / reaction
 ENSG00000135968 GCC2 / Q8IWJ2 / GRIP and coiled-coil domain containing 2  / reaction
 ENSG00000197081 IGF2R / P11717 / insulin like growth factor 2 receptor  / complex
 ENSG00000151532 VTI1A / Q96AJ9 / vesicle transport through interaction with t-SNAREs 1A  / reaction






 

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