ENSG00000102038


Homo sapiens

Features
Gene ID: ENSG00000102038
  
Biological name :SMARCA1
  
Synonyms : P28370 / SMARCA1 / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: q26.1
Gene start: 129446501
Gene end: 129523500
  
Corresponding Affymetrix probe sets: 203873_at (Human Genome U133 Plus 2.0 Array)   203874_s_at (Human Genome U133 Plus 2.0 Array)   203875_at (Human Genome U133 Plus 2.0 Array)   215294_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000360163
Ensembl peptide - ENSP00000360164
Ensembl peptide - ENSP00000360162
NCBI entrez gene - 6594     See in Manteia.
OMIM - 300012
RefSeq - XM_017029751
RefSeq - NM_001282875
RefSeq - NM_003069
RefSeq - XM_005262461
RefSeq - XM_005262462
RefSeq - XM_006724782
RefSeq - XM_017029750
RefSeq - NM_001282874
RefSeq Peptide - NP_003060
RefSeq Peptide - NP_001269803
RefSeq Peptide - NP_001269804
swissprot - B7ZLQ5
swissprot - P28370
swissprot - A0A0A0MRP6
Ensembl - ENSG00000102038
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 smarca1ENSDARG00000012776Danio rerio
 SMARCA1ENSGALG00000008431Gallus gallus
 Q6PGB8ENSMUSG00000031099Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O60264 / SMARCA5 / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5ENSG0000015314779
CHD1L / Q86WJ1 / chromodomain helicase DNA binding protein 1 likeENSG0000013177826


Protein motifs (from Interpro)
Interpro ID Name
 IPR000330  SNF2-related, N-terminal domain
 IPR001005  SANT/Myb domain
 IPR001650  Helicase, C-terminal
 IPR009057  Homeobox-like domain superfamily
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR015194  ISWI, HAND domain
 IPR015195  SLIDE domain
 IPR017884  SANT domain
 IPR020838  DBINO domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR029915  ISWI family
 IPR036306  ISWI, HAND domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000733 DNA strand renaturation IEA
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006338 chromatin remodeling IEA
 biological_processGO:0006351 transcription, DNA-templated IMP
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0030182 neuron differentiation IEA
 biological_processGO:0043044 ATP-dependent chromatin remodeling IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IMP
 biological_processGO:2000177 regulation of neural precursor cell proliferation IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0016589 NURF complex IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0090537 CERF complex IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008094 DNA-dependent ATPase activity IDA
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0031491 nucleosome binding IEA
 molecular_functionGO:0036310 annealing helicase activity IDA
 molecular_functionGO:0070615 nucleosome-dependent ATPase activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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