ENSG00000131778


Homo sapiens

Features
Gene ID: ENSG00000131778
  
Biological name :CHD1L
  
Synonyms : CHD1L / chromodomain helicase DNA binding protein 1 like / Q86WJ1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q21.1
Gene start: 147242641
Gene end: 147295766
  
Corresponding Affymetrix probe sets: 1556988_s_at (Human Genome U133 Plus 2.0 Array)   207645_s_at (Human Genome U133 Plus 2.0 Array)   212539_at (Human Genome U133 Plus 2.0 Array)   238070_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000358262
Ensembl peptide - ENSP00000355100
Ensembl peptide - ENSP00000358263
Ensembl peptide - ENSP00000491225
Ensembl peptide - ENSP00000482764
Ensembl peptide - ENSP00000480553
Ensembl peptide - ENSP00000477985
Ensembl peptide - ENSP00000389031
NCBI entrez gene - 9557     See in Manteia.
OMIM - 613039
RefSeq - XM_017002864
RefSeq - NM_001256336
RefSeq - NM_001256337
RefSeq - NM_001256338
RefSeq - NM_001348452
RefSeq - NM_001348453
RefSeq - NM_001348457
RefSeq - NM_001348462
RefSeq - NM_004284
RefSeq - NM_024568
RefSeq - XM_006711639
RefSeq - XM_017002858
RefSeq - XM_017002859
RefSeq - XM_017002860
RefSeq - XM_017002861
RefSeq - XM_017002862
RefSeq - XM_017002863
RefSeq Peptide - NP_001243267
RefSeq Peptide - NP_001335381
RefSeq Peptide - NP_001335382
RefSeq Peptide - NP_001335385
RefSeq Peptide - NP_001335386
RefSeq Peptide - NP_001335387
RefSeq Peptide - NP_001335388
RefSeq Peptide - NP_001335389
RefSeq Peptide - NP_001335390
RefSeq Peptide - NP_001335393
RefSeq Peptide - NP_001335394
RefSeq Peptide - NP_001335395
RefSeq Peptide - NP_004275
RefSeq Peptide - NP_078844
RefSeq Peptide - NP_001243265
RefSeq Peptide - NP_001243266
RefSeq Peptide - NP_001335391
RefSeq Peptide - NP_001335392
swissprot - A0A1W2PP16
swissprot - A0A0A0MSH9
swissprot - A0A0A0MRH8
swissprot - A0A087WZM7
swissprot - A0A087WWW4
swissprot - A0A087WTM4
swissprot - Q86WJ1
Ensembl - ENSG00000131778
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chd1lENSDARG00000015471Danio rerio
 CHD1LENSGALG00000015038Gallus gallus
 Chd1lENSMUSG00000028089Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O60264 / SMARCA5 / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5ENSG0000015314731
P28370 / SMARCA1 / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1ENSG0000010203831


Protein motifs (from Interpro)
Interpro ID Name
 IPR000330  SNF2-related, N-terminal domain
 IPR001650  Helicase, C-terminal
 IPR002464  DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
 IPR002589  Macro domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR031053  Chromodomain-helicase-DNA-binding protein 1-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000717 nucleotide-excision repair, DNA duplex unwinding TAS
 biological_processGO:0006281 DNA repair TAS
 biological_processGO:0006293 nucleotide-excision repair, preincision complex stabilization TAS
 biological_processGO:0006294 nucleotide-excision repair, preincision complex assembly TAS
 biological_processGO:0006295 nucleotide-excision repair, DNA incision, 3"-to lesion TAS
 biological_processGO:0006296 nucleotide-excision repair, DNA incision, 5"-to lesion TAS
 biological_processGO:0006338 chromatin remodeling IDA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0032508 DNA duplex unwinding IEA
 biological_processGO:0033683 nucleotide-excision repair, DNA incision TAS
 biological_processGO:0043044 ATP-dependent chromatin remodeling IEA
 biological_processGO:0070911 global genome nucleotide-excision repair TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004003 ATP-dependent DNA helicase activity TAS
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016887 ATPase activity IMP


Pathways (from Reactome)
Pathway description
Formation of Incision Complex in GG-NER
Dual Incision in GG-NER


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000100387 RBX1 / P62877 / ring-box 1  / complex / reaction
 ENSG00000134574 DDB2 / Q92466 / damage specific DNA binding protein 2  / complex / reaction
 ENSG00000154767 XPC / Q01831 / XPC complex subunit, DNA damage recognition and repair factor  / reaction / complex
 ENSG00000167986 DDB1 / Q16531 / damage specific DNA binding protein 1  / complex / reaction
 ENSG00000158290 CUL4B / Q13620 / cullin 4B  / complex / reaction
 ENSG00000139842 CUL4A / Q13619 / cullin 4A  / complex / reaction
 ENSG00000119318 P54727 / RAD23B / RAD23 homolog B, nucleotide excision repair protein  / reaction / complex
 ENSG00000143799 PARP1 / P09874 / poly(ADP-ribose) polymerase 1  / reaction / complex
 ENSG00000147400 CETN2 / P41208 / centrin 2  / reaction / complex
 ENSG00000136936 XPA / P23025 / XPA, DNA damage recognition and repair factor  / complex / reaction






 

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