ENSG00000103549


Homo sapiens

Features
Gene ID: ENSG00000103549
  
Biological name :RNF40
  
Synonyms : O75150 / ring finger protein 40 / RNF40
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p11.2
Gene start: 30761745
Gene end: 30776307
  
Corresponding Affymetrix probe sets: 206845_s_at (Human Genome U133 Plus 2.0 Array)   217642_at (Human Genome U133 Plus 2.0 Array)   239801_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000460142
Ensembl peptide - ENSP00000457697
Ensembl peptide - ENSP00000473507
Ensembl peptide - ENSP00000477937
Ensembl peptide - ENSP00000325677
Ensembl peptide - ENSP00000350563
Ensembl peptide - ENSP00000455180
Ensembl peptide - ENSP00000455678
Ensembl peptide - ENSP00000456538
NCBI entrez gene - 9810     See in Manteia.
OMIM - 607700
RefSeq - XM_011545997
RefSeq - NM_001207033
RefSeq - NM_001207034
RefSeq - NM_001286572
RefSeq - NM_014771
RefSeq Peptide - NP_055586
RefSeq Peptide - NP_001193962
RefSeq Peptide - NP_001193963
RefSeq Peptide - NP_001273501
swissprot - A0A024QZG0
swissprot - A0A087WTK2
swissprot - H3BP71
swissprot - H3BQ99
swissprot - H3BUL6
swissprot - H3BS50
swissprot - I3L332
swissprot - O75150
swissprot - R4GN66
Ensembl - ENSG00000103549
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rnf40ENSDARG00000054201Danio rerio
 Rnf40ENSMUSG00000030816Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RNF20 / Q5VTR2 / ring finger protein 20ENSG0000015582757


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013956  E3 ubiquitin ligase Bre1
 IPR017907  Zinc finger, RING-type, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process ISS
 biological_processGO:0010390 histone monoubiquitination IEA
 biological_processGO:0016567 protein ubiquitination TAS
 biological_processGO:0033523 histone H2B ubiquitination IDA
 biological_processGO:0043434 response to peptide hormone IEA
 biological_processGO:1900364 negative regulation of mRNA polyadenylation IMP
 biological_processGO:1901800 positive regulation of proteasomal protein catabolic process IEA
 biological_processGO:1902916 positive regulation of protein polyubiquitination IEA
 biological_processGO:2001168 positive regulation of histone H2B ubiquitination IMP
 cellular_componentGO:0000151 ubiquitin ligase complex IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0019898 extrinsic component of membrane IEA
 cellular_componentGO:0033503 HULC complex IDA
 cellular_componentGO:0043005 neuron projection ISS
 cellular_componentGO:0043679 axon terminus IEA
 molecular_functionGO:0003730 mRNA 3"-UTR binding IDA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0017075 syntaxin-1 binding IEA
 molecular_functionGO:0031624 ubiquitin conjugating enzyme binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
E3 ubiquitin ligases ubiquitinate target proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000103549 RNF40 / O75150 / ring finger protein 40  / complex
 ENSG00000155827 RNF20 / Q5VTR2 / ring finger protein 20  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr