ENSMUSG00000030816


Mus musculus

Features
Gene ID: ENSMUSG00000030816
  
Biological name :Rnf40
  
Synonyms : Q3U319 / ring finger protein 40 / Rnf40
  
Possible biological names infered from orthology : O75150
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: F3
Gene start: 127588767
Gene end: 127604799
  
Corresponding Affymetrix probe sets: 10557716 (MoGene1.0st)   1438191_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000146004
Ensembl peptide - ENSMUSP00000146310
Ensembl peptide - ENSMUSP00000033088
NCBI entrez gene - 233900     See in Manteia.
MGI - MGI:2142048
RefSeq - XM_006507749
RefSeq - XM_006507750
RefSeq - XM_006507751
RefSeq - NM_172281
RefSeq Peptide - NP_758485
swissprot - Q3U319
swissprot - A0A0U1RPJ4
swissprot - A0A0X1KG60
Ensembl - ENSMUSG00000030816
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rnf40ENSDARG00000054201Danio rerio
 RNF40ENSG00000103549Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rnf20 / Q5DTM8 / ring finger protein 20 / Q5VTR2*ENSMUSG0000002830957


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013956  E3 ubiquitin ligase Bre1
 IPR017907  Zinc finger, RING-type, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0010390 histone monoubiquitination IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0033523 histone H2B ubiquitination IEA
 biological_processGO:0043434 response to peptide hormone IEA
 biological_processGO:1900364 negative regulation of mRNA polyadenylation IEA
 biological_processGO:1901800 positive regulation of proteasomal protein catabolic process IEA
 biological_processGO:1902916 positive regulation of protein polyubiquitination IEA
 biological_processGO:2001168 positive regulation of histone H2B ubiquitination IMP
 cellular_componentGO:0000151 ubiquitin ligase complex IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0019898 extrinsic component of membrane IEA
 cellular_componentGO:0033503 HULC complex IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043679 axon terminus IEA
 molecular_functionGO:0003730 mRNA 3"-UTR binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0017075 syntaxin-1 binding IEA
 molecular_functionGO:0031624 ubiquitin conjugating enzyme binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
E3 ubiquitin ligases ubiquitinate target proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000030816 Rnf40 / Q3U319 / ring finger protein 40 / O75150*  / complex
 ENSMUSG00000028309 Rnf20 / Q5DTM8 / ring finger protein 20 / Q5VTR2*  / complex






 

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contact: otassy@igbmc.fr