ENSG00000104524


Homo sapiens

Features
Gene ID: ENSG00000104524
  
Biological name :PYCR3
  
Synonyms : PYCR3 / pyrroline-5-carboxylate reductase 3 / Q53H96
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: q24.3
Gene start: 143603913
Gene end: 143609773
  
Corresponding Affymetrix probe sets: 218944_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000478138
Ensembl peptide - ENSP00000366802
Ensembl peptide - ENSP00000480945
Ensembl peptide - ENSP00000401804
Ensembl peptide - ENSP00000404493
Ensembl peptide - ENSP00000220966
NCBI entrez gene - 65263     See in Manteia.
OMIM - 616408
RefSeq - NM_023078
RefSeq Peptide - NP_075566
swissprot - A0A087WTU2
swissprot - B5MD87
swissprot - Q53H96
swissprot - F8WEI0
swissprot - A0A0A0MQS1
Ensembl - ENSG00000104524
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pycr3ENSDARG00000015236Danio rerio
 PYCR3ENSGALG00000033828Gallus gallus
 PycrlENSMUSG00000022571Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PYCR1 / P32322 / pyrroline-5-carboxylate reductase 1ENSG0000018301042
PYCR2 / Q96C36 / pyrroline-5-carboxylate reductase 2ENSG0000014381142
AL117348.2ENSG0000025583530


Protein motifs (from Interpro)
Interpro ID Name
 IPR000304  Pyrroline-5-carboxylate reductase
 IPR008927  6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
 IPR028939  Pyrroline-5-carboxylate reductase, catalytic, N-terminal
 IPR029036  Pyrroline-5-carboxylate reductase, dimerisation domain
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006561 proline biosynthetic process IEA
 biological_processGO:0008652 cellular amino acid biosynthetic process TAS
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0055129 L-proline biosynthetic process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0004735 pyrroline-5-carboxylate reductase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Amino acid synthesis and interconversion (transamination)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000104524 PYCR3 / Q53H96 / pyrroline-5-carboxylate reductase 3  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr