ENSMUSG00000022571


Mus musculus

Features
Gene ID: ENSMUSG00000022571
  
Biological name :Pycrl
  
Synonyms : Pycrl / Pyrroline-5-carboxylate reductase 3 / Q9DCC4
  
Possible biological names infered from orthology : PYCR3 / Q53H96
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: D3
Gene start: 75916477
Gene end: 75921560
  
Corresponding Affymetrix probe sets: 10429666 (MoGene1.0st)   1416400_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000049605
NCBI entrez gene - 66194     See in Manteia.
MGI - MGI:1913444
RefSeq - NM_025412
RefSeq - XM_006521252
RefSeq Peptide - NP_079688
swissprot - Q9DCC4
Ensembl - ENSMUSG00000022571
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pycr3ENSDARG00000015236Danio rerio
 PYCR3ENSGALG00000033828Gallus gallus
 PYCR3ENSG00000104524Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pycr2 / Q922Q4 / pyrroline-5-carboxylate reductase family, member 2 / Q96C36* / AL117348.2* / pyrroline-5-carboxylate reductase 2*ENSMUSG0000002652042
Pycr1 / Q922W5 / pyrroline-5-carboxylate reductase 1 / P32322*ENSMUSG0000002514040


Protein motifs (from Interpro)
Interpro ID Name
 IPR000304  Pyrroline-5-carboxylate reductase
 IPR008927  6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
 IPR028939  Pyrroline-5-carboxylate reductase, catalytic, N-terminal
 IPR029036  Pyrroline-5-carboxylate reductase, dimerisation domain
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006561 proline biosynthetic process IEA
 biological_processGO:0008652 cellular amino acid biosynthetic process IEA
 biological_processGO:0009972 cytidine deamination ISO
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0055129 L-proline biosynthetic process ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol ISS
 molecular_functionGO:0004126 cytidine deaminase activity ISO
 molecular_functionGO:0004735 pyrroline-5-carboxylate reductase activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
Amino acid synthesis and interconversion (transamination)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000022571 Pycrl / Q9DCC4 / Pyrroline-5-carboxylate reductase 3 / PYCR3* / Q53H96*  / complex






 

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