ENSG00000105419


Homo sapiens

Features
Gene ID: ENSG00000105419
  
Biological name :MEIS3
  
Synonyms : MEIS3 / Meis homeobox 3 / Q99687
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.32
Gene start: 47403124
Gene end: 47419523
  
Corresponding Affymetrix probe sets: 1569402_at (Human Genome U133 Plus 2.0 Array)   228327_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000454073
Ensembl peptide - ENSP00000475941
Ensembl peptide - ENSP00000476248
Ensembl peptide - ENSP00000333552
Ensembl peptide - ENSP00000388667
Ensembl peptide - ENSP00000452854
Ensembl peptide - ENSP00000453249
Ensembl peptide - ENSP00000453307
Ensembl peptide - ENSP00000453757
Ensembl peptide - ENSP00000453934
NCBI entrez gene - 56917     See in Manteia.
RefSeq - XM_017027011
RefSeq - NM_001009813
RefSeq - NM_001301059
RefSeq - NM_020160
RefSeq - XM_011527136
RefSeq - XM_011527138
RefSeq - XM_011527139
RefSeq - XM_011527140
RefSeq Peptide - NP_001009813
RefSeq Peptide - NP_001287988
RefSeq Peptide - NP_064545
swissprot - A0A024R0W2
swissprot - H0YLL0
swissprot - H0YMV2
swissprot - H0YNA8
swissprot - H3BLU4
swissprot - U3KQJ9
swissprot - A0A024R0S2
swissprot - U3KQV2
swissprot - Q59FK5
swissprot - Q99687
Ensembl - ENSG00000105419
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 meis3ENSDARG00000002795Danio rerio
 Meis3ENSMUSG00000041420Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MEIS2 / O14770 / Meis homeobox 2ENSG0000013413862
MEIS1 / O00470 / Meis homeobox 1ENSG0000014399560
PKNOX2 / Q96KN3 / PBX/knotted 1 homeobox 2ENSG0000016549533
P55347 / PKNOX1 / PBX/knotted 1 homeobox 1ENSG0000016019931
TGIF1 / Q15583 / TGFB induced factor homeobox 1ENSG0000017742616
TGIF2 / Q9GZN2 / TGFB induced factor homeobox 2ENSG0000011870710
Q8IUE0 / TGIF2LY / TGFB induced factor homeobox 2 like, Y-linkedENSG000001766799
Q8IUE1 / TGIF2LX / TGFB induced factor homeobox 2 like, X-linkedENSG000001537799


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR008422  Homeobox KN domain
 IPR009057  Homeobox-like domain superfamily
 IPR032453  Homeobox protein PKNOX/Meis, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0051897 positive regulation of protein kinase B signaling IEA
 biological_processGO:2001234 negative regulation of apoptotic signaling pathway IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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