ENSG00000165495


Homo sapiens

Features
Gene ID: ENSG00000165495
  
Biological name :PKNOX2
  
Synonyms : PBX/knotted 1 homeobox 2 / PKNOX2 / Q96KN3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q24.2
Gene start: 125164687
Gene end: 125433389
  
Corresponding Affymetrix probe sets: 219046_s_at (Human Genome U133 Plus 2.0 Array)   222171_s_at (Human Genome U133 Plus 2.0 Array)   222185_at (Human Genome U133 Plus 2.0 Array)   63305_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000453374
Ensembl peptide - ENSP00000298282
Ensembl peptide - ENSP00000431599
Ensembl peptide - ENSP00000434255
Ensembl peptide - ENSP00000434377
NCBI entrez gene - 63876     See in Manteia.
OMIM - 613066
RefSeq - XM_017018111
RefSeq - XM_006718894
RefSeq - XM_011542944
RefSeq - XM_011542945
RefSeq - XM_011542946
RefSeq - XM_011542947
RefSeq - XM_017018110
RefSeq - NM_022062
RefSeq - XM_005271642
RefSeq - XM_005271643
RefSeq Peptide - NP_071345
swissprot - E9PRB6
swissprot - E9PQS4
swissprot - H0YLX0
swissprot - E9PKL2
swissprot - Q96KN3
Ensembl - ENSG00000165495
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pknox2ENSDARG00000055349Danio rerio
 PKNOX2ENSGALG00000043103Gallus gallus
 Pknox2ENSMUSG00000035934Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P55347 / PKNOX1 / PBX/knotted 1 homeobox 1ENSG0000016019958
MEIS2 / O14770 / Meis homeobox 2ENSG0000013413833
MEIS3 / Q99687 / Meis homeobox 3ENSG0000010541930
MEIS1 / O00470 / Meis homeobox 1ENSG0000014399530
TGIF1 / Q15583 / TGFB induced factor homeobox 1ENSG0000017742614
TGIF2 / Q9GZN2 / TGFB induced factor homeobox 2ENSG0000011870710
Q8IUE1 / TGIF2LX / TGFB induced factor homeobox 2 like, X-linkedENSG0000015377910
Q8IUE0 / TGIF2LY / TGFB induced factor homeobox 2 like, Y-linkedENSG000001766799


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR008422  Homeobox KN domain
 IPR009057  Homeobox-like domain superfamily
 IPR032453  Homeobox protein PKNOX/Meis, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IEA
 cellular_componentGO:0045171 intercellular bridge IDA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003785 actin monomer binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr