ENSMUSG00000035934


Mus musculus

Features
Gene ID: ENSMUSG00000035934
  
Biological name :Pknox2
  
Synonyms : Homeobox protein PKNOX2 / Pknox2 / Q8BG99
  
Possible biological names infered from orthology : PBX/knotted 1 homeobox 2 / Q96KN3
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: A4
Gene start: 36890982
Gene end: 37147407
  
Corresponding Affymetrix probe sets: 10592251 (MoGene1.0st)   1428017_at (Mouse Genome 430 2.0 Array)   1433907_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000138866
Ensembl peptide - ENSMUSP00000139728
Ensembl peptide - ENSMUSP00000140793
Ensembl peptide - ENSMUSP00000139976
Ensembl peptide - ENSMUSP00000035806
Ensembl peptide - ENSMUSP00000079578
Ensembl peptide - ENSMUSP00000135581
Ensembl peptide - ENSMUSP00000135641
NCBI entrez gene - 208076     See in Manteia.
MGI - MGI:2445415
RefSeq - NM_148950
RefSeq - XM_006510125
RefSeq - XM_006510126
RefSeq - XM_006510127
RefSeq - XM_011242440
RefSeq - XM_017313255
RefSeq - NM_001029838
RefSeq - XM_006510124
RefSeq Peptide - NP_001025009
RefSeq Peptide - NP_683752
swissprot - Q8BG99
swissprot - A0A087WPZ3
swissprot - H3BL39
swissprot - A0A087WPD3
swissprot - A0A087WRV9
swissprot - V9GWW7
Ensembl - ENSMUSG00000035934
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pknox2ENSDARG00000055349Danio rerio
 PKNOX2ENSGALG00000043103Gallus gallus
 PKNOX2ENSG00000165495Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O70477 / Pknox1 / Homeobox protein PKNOX1 / P55347* / PBX/knotted 1 homeobox 1*ENSMUSG0000000670558
Meis2 / P97367 / Homeobox protein Meis2 / O14770* / Meis homeobox 2*ENSMUSG0000002721032
Meis1 / Q60954 / Homeobox protein Meis1 / O00470* / Meis homeobox 1*ENSMUSG0000002016031
Meis3 / P97368 / Homeobox protein Meis3 / Q99687* / Meis homeobox 3*ENSMUSG0000004142030
Tgif1 / P70284 / TGFB-induced factor homeobox 1 / Q15583*ENSMUSG0000004740712
Tgif2 / Q8C0Y1 / TGFB-induced factor homeobox 2 / Q9GZN2*ENSMUSG0000006217510
Tgif2lx1 / TGFB-induced factor homeobox 2-like, X-linked 1 / Q8IUE1* / Q8IUE0* / TGIF2LX* / TGIF2LY* / TGFB induced factor homeobox 2 like, X-linked* / TGFB induced factor homeobox 2 like, Y-linked*ENSMUSG000001001337
Tgif2lx2 / TGFB-induced factor homeobox 2-like, X-linked 2 / Q8IUE1* / Q8IUE0* / TGIF2LX* / TGIF2LY* / TGFB induced factor homeobox 2 like, X-linked* / TGFB induced factor homeobox 2 like, Y-linked*ENSMUSG000001001947


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR008422  Homeobox KN domain
 IPR009057  Homeobox-like domain superfamily
 IPR032453  Homeobox protein PKNOX/Meis, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IGI
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0015629 actin cytoskeleton IDA
 cellular_componentGO:0015630 microtubule cytoskeleton IDA
 cellular_componentGO:0045171 intercellular bridge ISO
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IC
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003785 actin monomer binding IDA
 molecular_functionGO:0043565 sequence-specific DNA binding IGI
 molecular_functionGO:0051015 actin filament binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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