ENSG00000106038


Homo sapiens

Features
Gene ID: ENSG00000106038
  
Biological name :EVX1
  
Synonyms : even-skipped homeobox 1 / EVX1 / P49640
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: p15.2
Gene start: 27242700
Gene end: 27250493
  
Corresponding Affymetrix probe sets: 207914_x_at (Human Genome U133 Plus 2.0 Array)   231706_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000222761
Ensembl peptide - ENSP00000419266
Ensembl peptide - ENSP00000463759
NCBI entrez gene - 2128     See in Manteia.
OMIM - 142996
RefSeq - NM_001304519
RefSeq - NM_001304520
RefSeq - NM_001989
RefSeq Peptide - NP_001980
RefSeq Peptide - NP_001291448
RefSeq Peptide - NP_001291449
swissprot - P49640
swissprot - J3QQJ1
swissprot - F8W9J5
Ensembl - ENSG00000106038
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 evx1ENSDARG00000099365Danio rerio
 evx1ENSDARG00000100087Danio rerio
 EVX1ENSGALG00000037310Gallus gallus
 Evx1ENSMUSG00000005503Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EVX2 / Q03828 / even-skipped homeobox 2ENSG0000017427952
MNX1 / P50219 / motor neuron and pancreas homeobox 1ENSG0000013067520
NKX1-1 / Q15270 / NK1 homeobox 1ENSG0000023560819
GBX1 / Q14549 / gastrulation brain homeobox 1ENSG0000016490016
NKX1-2 / Q9UD57 / NK1 homeobox 2ENSG0000022954415
GBX2 / P52951 / gastrulation brain homeobox 2ENSG0000016850515
MEOX2 / P50222 / mesenchyme homeobox 2ENSG0000010651115
VENTX / O95231 / VENT homeoboxENSG0000015165014
MEOX1 / P50221 / mesenchyme homeobox 1ENSG0000000510212


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0009792 embryo development ending in birth or egg hatching IEA
 biological_processGO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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