ENSMUSG00000005503


Mus musculus

Features
Gene ID: ENSMUSG00000005503
  
Biological name :Evx1
  
Synonyms : Evx1 / Homeobox even-skipped homolog protein 1 / P23683
  
Possible biological names infered from orthology : even-skipped homeobox 1 / P49640
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: B3
Gene start: 52313498
Gene end: 52318378
  
Corresponding Affymetrix probe sets: 10538310 (MoGene1.0st)   1421627_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000031787
Ensembl peptide - ENSMUSP00000119111
NCBI entrez gene - 14028     See in Manteia.
MGI - MGI:95461
RefSeq - NM_007966
RefSeq - XM_006505516
RefSeq Peptide - NP_031992
swissprot - F6R8N2
swissprot - P23683
Ensembl - ENSMUSG00000005503
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 evx1ENSDARG00000099365Danio rerio
 evx1ENSDARG00000100087Danio rerio
 EVX1ENSGALG00000037310Gallus gallus
 EVX1ENSG00000106038Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Evx2 / P49749 / Homeobox even-skipped homolog protein 2 / Q03828* / even-skipped homeobox 2*ENSMUSG0000000181548
Nkx1-1 / NK1 transcription factor-related protein 1 / Q15270* / NK1 homeobox 1*ENSMUSG0000002911219
Mnx1 / Q9QZW9 / motor neuron and pancreas homeobox 1 / P50219*ENSMUSG0000000156619
Nkx1-2 / P42580 / NK1 transcription factor-related protein 2 / Q9UD57* / NK1 homeobox 2*ENSMUSG0000004852815
Gbx1 / P82976 / Homeobox protein GBX-1 / Q14549* / gastrulation brain homeobox 1*ENSMUSG0000006772414
Meox2 / P32443 / Homeobox protein MOX-2 / P50222* / mesenchyme homeobox 2*ENSMUSG0000003614414
Gbx2 / P48031 / Homeobox protein GBX-2 / P52951* / gastrulation brain homeobox 2*ENSMUSG0000003448614
Meox1 / P32442 / Homeobox protein MOX-1 / P50221* / mesenchyme homeobox 1*ENSMUSG0000000149313


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0009792 embryo development ending in birth or egg hatching IMP
 biological_processGO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002085 abnormal embryonic tissue morphology "structural abnormality or development of any embryonic tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Il11ra1tm2Gos/Il11ra1tm2Gos
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0004100 abnormal spinal cord interneuron morphology "malformation or absence of neurons that exclusively interact with other neurons in the spinal cord" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Adatm1Vlr/Adatm1Vlr
Genetic Background: either: 129P2/OlaHsd-Adatm1Vlr or (involves: (129P2/OlaHsd * FVB/N)

 MP:0011094 complete embryonic lethality before implantation "death of all organisms of a given genotype in a population between fertilization and implantation (Mus: E0 to less than E4.5)" [MGI:csmith]
Show

Allelic Composition: Il11ra1tm2Gos/Il11ra1tm2Gos
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0012102 absent trophectoderm "absence of the outermost layer of cells in the blastodermic vesicle, which will develop into the trophoblast layer and then contact the endometrium and take part in establishing the embryo s means of nutrition" [MGI:anna]
Show

Allelic Composition: Il11ra1tm2Gos/Il11ra1tm2Gos
Genetic Background: involves: 129S2/SvPas * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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