ENSG00000106511


Homo sapiens

Features
Gene ID: ENSG00000106511
  
Biological name :MEOX2
  
Synonyms : MEOX2 / mesenchyme homeobox 2 / P50222
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: p21.2
Gene start: 15611212
Gene end: 15686812
  
Corresponding Affymetrix probe sets: 206201_s_at (Human Genome U133 Plus 2.0 Array)   206202_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000262041
NCBI entrez gene - 4223     See in Manteia.
OMIM - 600535
RefSeq - NM_005924
RefSeq Peptide - NP_005915
swissprot - P50222
Ensembl - ENSG00000106511
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 meox2aENSDARG00000040911Danio rerio
 meox2bENSDARG00000061818Danio rerio
 MEOX2ENSGALG00000010794Gallus gallus
 Meox2ENSMUSG00000036144Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MEOX1 / P50221 / mesenchyme homeobox 1ENSG0000000510238
EVX1 / P49640 / even-skipped homeobox 1ENSG0000010603820
MNX1 / P50219 / motor neuron and pancreas homeobox 1ENSG0000013067519
GBX2 / P52951 / gastrulation brain homeobox 2ENSG0000016850518
GBX1 / Q14549 / gastrulation brain homeobox 1ENSG0000016490018
NKX1-1 / Q15270 / NK1 homeobox 1ENSG0000023560817
EVX2 / Q03828 / even-skipped homeobox 2ENSG0000017427917
NKX1-2 / Q9UD57 / NK1 homeobox 2ENSG0000022954416
VENTX / O95231 / VENT homeoboxENSG0000015165014


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001757 somite specification IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development TAS
 biological_processGO:0007519 skeletal muscle tissue development IEA
 biological_processGO:0008015 blood circulation TAS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0060021 roof of mouth development IEA
 biological_processGO:0060173 limb development IEA
 biological_processGO:0061053 somite development IBA
 biological_processGO:0070997 neuron death IMP
 biological_processGO:0090051 negative regulation of cell migration involved in sprouting angiogenesis IGI
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IMP
 molecular_functionGO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding IMP
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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