ENSG00000229544


Homo sapiens

Features
Gene ID: ENSG00000229544
  
Biological name :NKX1-2
  
Synonyms : NK1 homeobox 2 / NKX1-2 / Q9UD57
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: q26.13
Gene start: 124445239
Gene end: 124450184
  
Corresponding Affymetrix probe sets: 230356_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000451945
NCBI entrez gene - 390010     See in Manteia.
RefSeq - NM_001146340
RefSeq Peptide - NP_001139812
swissprot - Q9UD57
Ensembl - ENSG00000229544
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nkx1.2laENSDARG00000006350Danio rerio
 Nkx1-2ENSMUSG00000048528Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NKX1-1 / Q15270 / NK1 homeobox 1ENSG0000023560849
MNX1 / P50219 / motor neuron and pancreas homeobox 1ENSG0000013067524
GBX1 / Q14549 / gastrulation brain homeobox 1ENSG0000016490020
GBX2 / P52951 / gastrulation brain homeobox 2ENSG0000016850519
EVX1 / P49640 / even-skipped homeobox 1ENSG0000010603819
EVX2 / Q03828 / even-skipped homeobox 2ENSG0000017427918
VENTX / O95231 / VENT homeoboxENSG0000015165017
MEOX1 / P50221 / mesenchyme homeobox 1ENSG0000000510216
MEOX2 / P50222 / mesenchyme homeobox 2ENSG0000010651116


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr