ENSG00000106052


Homo sapiens

Features
Gene ID: ENSG00000106052
  
Biological name :TAX1BP1
  
Synonyms : Q86VP1 / Tax1 binding protein 1 / TAX1BP1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: p15.2
Gene start: 27739331
Gene end: 27844564
  
Corresponding Affymetrix probe sets: 200976_s_at (Human Genome U133 Plus 2.0 Array)   200977_s_at (Human Genome U133 Plus 2.0 Array)   213786_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000395290
Ensembl peptide - ENSP00000411490
Ensembl peptide - ENSP00000477282
Ensembl peptide - ENSP00000444811
Ensembl peptide - ENSP00000412575
Ensembl peptide - ENSP00000265393
Ensembl peptide - ENSP00000379612
Ensembl peptide - ENSP00000386515
Ensembl peptide - ENSP00000391215
Ensembl peptide - ENSP00000391907
NCBI entrez gene - 8887     See in Manteia.
OMIM - 605326
RefSeq - XM_017012754
RefSeq - NM_001079864
RefSeq - NM_001206901
RefSeq - NM_001206902
RefSeq - NM_006024
RefSeq - XM_005249900
RefSeq Peptide - NP_006015
RefSeq Peptide - NP_001073333
RefSeq Peptide - NP_001193830
RefSeq Peptide - NP_001193831
swissprot - H7C3L5
swissprot - Q86VP1
swissprot - C9J7J4
swissprot - B8ZZD4
swissprot - V9GZ06
swissprot - C9JBZ7
swissprot - F8WBU9
Ensembl - ENSG00000106052
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tax1bp1aENSDARG00000098288Danio rerio
 tax1bp1bENSDARG00000056856Danio rerio
 TAX1BP1ENSGALG00000042822Gallus gallus
 Q3UKC1ENSMUSG00000004535Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9P1Z2 / CALCOCO1 / calcium binding and coiled-coil domain 1ENSG0000001282220
Q13137 / CALCOCO2 / calcium binding and coiled-coil domain 2ENSG0000013643619


Protein motifs (from Interpro)
Interpro ID Name
 IPR012852  Calcium binding and coiled-coil domain-like
 IPR013083  Zinc finger, RING/FYVE/PHD-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0010803 regulation of tumor necrosis factor-mediated signaling pathway TAS
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity ISS
 biological_processGO:0032480 negative regulation of type I interferon production TAS
 biological_processGO:0043066 negative regulation of apoptotic process TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019900 kinase binding ISS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Regulation of TNFR1 signaling
Negative regulators of DDX58/IFIH1 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000118503 P21580 / TNFAIP3 / TNF alpha induced protein 3  / complex
 ENSG00000183735 TBK1 / Q9UHD2 / TANK binding kinase 1  / reaction / complex
 ENSG00000263528 IKBKE / Q14164 / inhibitor of nuclear factor kappa B kinase subunit epsilon  / reaction / complex






 

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