ENSG00000107447


Homo sapiens

Features
Gene ID: ENSG00000107447
  
Biological name :DNTT
  
Synonyms : DNA nucleotidylexotransferase / DNTT / P04053
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q24.1
Gene start: 96304396
Gene end: 96338564
  
Corresponding Affymetrix probe sets: 1566362_at (Human Genome U133 Plus 2.0 Array)   1566363_at (Human Genome U133 Plus 2.0 Array)   210487_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000360216
Ensembl peptide - ENSP00000486733
NCBI entrez gene - 1791     See in Manteia.
OMIM - 187410
RefSeq - NM_001017520
RefSeq - NM_004088
RefSeq Peptide - NP_001017520
RefSeq Peptide - NP_004079
swissprot - P04053
Ensembl - ENSG00000107447
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dnttENSDARG00000104792Danio rerio
 DNTTENSGALG00000006983Gallus gallus
 DnttENSMUSG00000025014Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
POLM / Q9NP87 / DNA polymerase muENSG0000012267827
POLL / Q9UGP5 / DNA polymerase lambdaENSG0000016616923
POLB / P06746 / DNA polymerase betaENSG0000007050117


Protein motifs (from Interpro)
Interpro ID Name
 IPR001357  BRCT domain
 IPR001726  DNA nucleotidylexotransferase (TdT) / DNA-directed DNA/RNA polymerase mu
 IPR002054  DNA-directed DNA polymerase X
 IPR010996  DNA polymerase beta-like, N-terminal domain
 IPR018944  DNA polymerase lambda, fingers domain
 IPR019843  DNA polymerase family X, binding site
 IPR022312  DNA polymerase family X
 IPR027292  DNA nucleotidylexotransferase (TdT)
 IPR027421  DNA polymerase lambda lyase domain superfamily
 IPR028207  DNA polymerase beta, palm domain
 IPR029398  DNA polymerase beta, thumb domain
 IPR036420  BRCT domain superfamily
 IPR037160  DNA polymerase, thumb domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006259 DNA metabolic process IDA
 biological_processGO:0006304 DNA modification IEA
 biological_processGO:0033198 response to ATP IEA
 biological_processGO:0071897 DNA biosynthetic process IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0000791 euchromatin IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016363 nuclear matrix IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003887 DNA-directed DNA polymerase activity IEA
 molecular_functionGO:0003912 DNA nucleotidylexotransferase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity IEA
 molecular_functionGO:0034061 DNA polymerase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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