ENSG00000107872


Homo sapiens

Features
Gene ID: ENSG00000107872
  
Biological name :FBXL15
  
Synonyms : F-box and leucine rich repeat protein 15 / FBXL15 / Q9H469
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q24.32
Gene start: 102419189
Gene end: 102423136
  
Corresponding Affymetrix probe sets: 218938_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000405961
Ensembl peptide - ENSP00000403646
Ensembl peptide - ENSP00000411435
Ensembl peptide - ENSP00000224862
Ensembl peptide - ENSP00000358972
Ensembl peptide - ENSP00000392215
NCBI entrez gene - 79176     See in Manteia.
OMIM - 610287
RefSeq - XM_017016631
RefSeq - NM_024326
RefSeq - XM_005270149
RefSeq - XM_005270150
RefSeq - XM_005270151
RefSeq Peptide - NP_077302
swissprot - X6RHD7
swissprot - X6RJB2
swissprot - X6RGT4
swissprot - Q9H469
swissprot - X6RCZ8
swissprot - A0A0C4DFV0
Ensembl - ENSG00000107872
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fbxl15ENSDARG00000005284Danio rerio
 FBXL15ENSGALG00000005684Gallus gallus
 Fbxl15ENSMUSG00000025226Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FBXL13 / Q8NEE6 / F-box and leucine rich repeat protein 13ENSG0000016104026
FBXL2 / Q9UKC9 / F-box and leucine rich repeat protein 2ENSG0000015355824
FBXL20 / Q96IG2 / F-box and leucine rich repeat protein 20ENSG0000010830623
FBXL7 / Q9UJT9 / F-box and leucine rich repeat protein 7ENSG0000018358022
FBXL4 / Q9UKA2 / F-box and leucine rich repeat protein 4ENSG0000011223420
FBXL14 / Q8N1E6 / F-box and leucine rich repeat protein 14ENSG0000017182320
FBXL16 / Q8N461 / F-box and leucine rich repeat protein 16ENSG0000012758519
FBXL17 / Q9UF56 / F-box and leucine rich repeat protein 17ENSG0000014574318
LRRC29 / Q8WV35 / leucine rich repeat containing 29ENSG0000012512212


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR001810  F-box domain
 IPR006553  Leucine-rich repeat, cysteine-containing subtype
 IPR032675  Leucine-rich repeat domain superfamily
 IPR036047  F-box-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000086 G2/M transition of mitotic cell cycle IMP
 biological_processGO:0000209 protein polyubiquitination TAS
 biological_processGO:0009953 dorsal/ventral pattern formation ISS
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0030282 bone mineralization IEA
 biological_processGO:0030513 positive regulation of BMP signaling pathway IMP
 biological_processGO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0019005 SCF ubiquitin ligase complex IDA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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