ENSG00000171823


Homo sapiens

Features
Gene ID: ENSG00000171823
  
Biological name :FBXL14
  
Synonyms : F-box and leucine rich repeat protein 14 / FBXL14 / Q8N1E6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: p13.33
Gene start: 1565993
Gene end: 1594165
  
Corresponding Affymetrix probe sets: 1553682_at (Human Genome U133 Plus 2.0 Array)   1553683_s_at (Human Genome U133 Plus 2.0 Array)   213145_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000344855
NCBI entrez gene - 144699     See in Manteia.
OMIM - 609081
RefSeq - NM_152441
RefSeq - XM_017018875
RefSeq Peptide - NP_689654
swissprot - Q8N1E6
Ensembl - ENSG00000171823
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fbxl14aENSDARG00000034497Danio rerio
 fbxl14bENSDARG00000045801Danio rerio
 FBXL14ENSGALG00000032159Gallus gallus
 Fbxl14ENSMUSG00000030019Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FBXL13 / Q8NEE6 / F-box and leucine rich repeat protein 13ENSG0000016104026
FBXL2 / Q9UKC9 / F-box and leucine rich repeat protein 2ENSG0000015355823
FBXL20 / Q96IG2 / F-box and leucine rich repeat protein 20ENSG0000010830622
FBXL16 / Q8N461 / F-box and leucine rich repeat protein 16ENSG0000012758520
FBXL7 / Q9UJT9 / F-box and leucine rich repeat protein 7ENSG0000018358019
FBXL17 / Q9UF56 / F-box and leucine rich repeat protein 17ENSG0000014574318
FBXL4 / Q9UKA2 / F-box and leucine rich repeat protein 4ENSG0000011223417
FBXL15 / Q9H469 / F-box and leucine rich repeat protein 15ENSG0000010787214
LRRC29 / Q8WV35 / leucine rich repeat containing 29ENSG0000012512211


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR001810  F-box domain
 IPR006553  Leucine-rich repeat, cysteine-containing subtype
 IPR032675  Leucine-rich repeat domain superfamily
 IPR036047  F-box-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination TAS
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0004842 ubiquitin-protein transferase activity TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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